MGP Database

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MGP003018

Ontology/Pathway Information

Entrez Gene ID6812
Gene Namesyntaxin binding protein 1
Gene Symbol STXBP1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 ISS:UniProtKBCcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005739 ISS:UniProtKBCmitochondrion
GO:0005654 IDA:HPACnucleoplasm
GO:0005886 IDA:UniProtKBCplasma membrane
GO:0031091 IDA:UniProtKBCplatelet alpha granule
GO:0043234 ISS:UniProtKBCprotein complex
GO:0042802 ISS:UniProtKBFidentical protein binding
GO:0044822 IDA:UniProtKBFpoly(A) RNA binding
GO:0000149 ISS:UniProtKBFSNARE binding
GO:0017075 IPI:UniProtKBFsyntaxin-1 binding
GO:0019905 IPI:UniProtKBFsyntaxin binding
GO:0007412 ISS:UniProtKBPaxon target recognition
GO:0006112 TAS:ReactomePenergy reserve metabolic process
GO:0014047 TAS:ReactomePglutamate secretion
GO:0060292 IEA:EnsemblPlong term synaptic depression
GO:0043524 IEA:EnsemblPnegative regulation of neuron apoptotic process
GO:0032229 ISS:UniProtKBPnegative regulation of synaptic transmission, GABAergic
GO:0007274 IEA:EnsemblPneuromuscular synaptic transmission
GO:0007269 TAS:ReactomePneurotransmitter secretion
GO:0070527 IMP:UniProtKBPplatelet aggregation
GO:0002576 IMP:UniProtKBPplatelet degranulation
GO:0045956 IEA:EnsemblPpositive regulation of calcium ion-dependent exocytosis
GO:0072659 IDA:UniProtKBPprotein localization to plasma membrane
GO:0050821 IEA:EnsemblPprotein stabilization
GO:0015031 IEA:UniProtKB-KWPprotein transport
GO:0050796 TAS:ReactomePregulation of insulin secretion
GO:0035542 TAS:ParkinsonsUK-UCLPregulation of SNARE complex assembly
GO:0031630 TAS:ParkinsonsUK-UCLPregulation of synaptic vesicle fusion to presynaptic membrane
GO:0010807 ISS:UniProtKBPregulation of synaptic vesicle priming
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0007268 TAS:ReactomePsynaptic transmission
GO:0016188 ISS:UniProtKBPsynaptic vesicle maturation
GO:0006904 IEA:EnsemblPvesicle docking involved in exocytosis
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_1505Integration of energy metabolism
REACT_111217Metabolism
REACT_18325Regulation of insulin secretion
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