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MGP003022

UniProt Annotations

Entry Information
Gene Namesulfotransferase family, cytosolic, 1C, member 2
Protein EntryST1C2_HUMAN
UniProt IDO00338
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=Short; IsoId=O00338-1; Sequence=Displayed; Name=Long; IsoId=O00338-2; Sequence=VSP_006303;
FunctionSulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of drugs, xenobiotic compounds, hormones, and neurotransmitters. May be involved in the activation of carcinogenic hyroxylamines. Shows activity towards p-nitrophenol and N-hydroxy-2-acetylamino-fluorene (N-OH-2AAF).
SimilarityBelongs to the sulfotransferase 1 family. {ECO:0000305}.
Subcellular LocationCytoplasm.
Tissue SpecificityFound in adult stomach, kidney and thyroid gland, and in fetal kidney and liver.
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