MGP Database

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MGP003028

Ontology/Pathway Information

Entrez Gene ID6833
Gene NameATP-binding cassette, sub-family C (CFTR/MRP), member 8
Gene Symbol ABCC8
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005886 TAS:ReactomeCplasma membrane
GO:0008076 IDA:BHF-UCLCvoltage-gated potassium channel complex
GO:0042626 IEA:InterProFATPase activity, coupled to transmembrane movement of substances
GO:0005524 TAS:ProtIncFATP binding
GO:0044325 IPI:BHF-UCLFion channel binding
GO:0015079 TAS:ProtIncFpotassium ion transmembrane transporter activity
GO:0008281 TAS:ProtIncFsulfonylurea receptor activity
GO:0005975 NAS:ProtIncPcarbohydrate metabolic process
GO:0006112 TAS:ReactomePenergy reserve metabolic process
GO:0071805 TAS:GOCPpotassium ion transmembrane transport
GO:0006813 TAS:ProtIncPpotassium ion transport
GO:0050796 TAS:ReactomePregulation of insulin secretion
GO:0007165 TAS:GOCPsignal transduction
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0007268 TAS:ReactomePsynaptic transmission
GO:0055085 TAS:ReactomePtransmembrane transport
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_15480ABC-family proteins mediated transport
REACT_75775ATP sensitive Potassium channels
REACT_1505Integration of energy metabolism
REACT_75918Inwardly rectifying K+ channels
REACT_111217Metabolism
REACT_13685Neuronal System
REACT_75908Potassium Channels
REACT_18325Regulation of insulin secretion
REACT_15518Transmembrane transport of small molecules
SMP Pathway Links
SMP IDDescription
SMP00296Acebutolol Action Pathway
SMP00297Alprenolol Action Pathway
SMP00665Amiodarone Action Pathway
SMP00376Amlodipine Action Pathway
SMP00664Arbutamine Action Pathway
SMP00298Atenolol Action Pathway
SMP00299Betaxolol Action Pathway
SMP00668Bevantolol Action Pathway
SMP00300Bisoprolol Action Pathway
SMP00657Bopindolol Action Pathway
SMP00670Bupranolol Action Pathway
SMP00658Carteolol Action Pathway
SMP00367Carvedilol Action Pathway
SMP00359Diltiazem Action Pathway
SMP00325Disopyramide Action Pathway
SMP00662Dobutamine Action Pathway
SMP00661Epinephrine Action Pathway
SMP00301Esmolol Action Pathway
SMP00377Felodipine Action Pathway
SMP00331Flecainide Action Pathway
SMP00326Fosphenytoin (Antiarrhythmic) Action Pathway
SMP00460Glibenclamide Action Pathway
SMP00461Gliclazide Action Pathway
SMP00332Ibutilide Action Pathway
SMP00663Isoprenaline Action Pathway
SMP00378Isradipine Action Pathway
SMP00368Labetalol Action Pathway
SMP00666Levobunolol Action Pathway
SMP00328Lidocaine (Antiarrhythmic) Action Pathway
SMP00667Metipranolol Action Pathway
SMP00302Metoprolol Action Pathway
SMP00329Mexiletine Action Pathway
SMP00588Muscle/Heart Contraction
SMP00303Nadolol Action Pathway
SMP00453Nateglinide Action Pathway
SMP00366Nebivolol Action Pathway
SMP00379Nifedipine Action Pathway
SMP00380Nimodipine Action Pathway
SMP00381Nisoldipine Action Pathway
SMP00382Nitrendipine Action Pathway
SMP00304Oxprenolol Action Pathway
SMP00643Pancreas Function
SMP00305Penbutolol Action Pathway
SMP00327Phenytoin (Antiarrhythmic) Action Pathway
SMP00306Pindolol Action Pathway
SMP00669Practolol Action Pathway
SMP00324Procainamide (Antiarrhythmic) Action Pathway
SMP00307Propranolol Action Pathway
SMP00323Quinidine Action Pathway
SMP00454Repaglinide Action Pathway
SMP00660Sotalol Action Pathway
SMP00659Timolol Action Pathway
SMP00330Tocainide Action Pathway
SMP00375Verapamil Action Pathway
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