MGP Database

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MGP003032

Record overview

MGPD IDMGP003032
Gene ID6843
SpeciesHomo sapiens (Human)
Gene Namevesicle-associated membrane protein 1 (synaptobrevin 1)
Gene Symbol VAMP1
SynonymsSYB1; SPAX1; VAMP-1;
Alternate namesvesicle-associated membrane protein 1; synaptobrevin 1; synaptobrevin-1;
Chromosome12
Map Location12p
SummarySynapotobrevins, syntaxins, and the synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Mutations in this gene are associated with autosomal dominant spastic ataxia 1. Multiple alternative splice variants have been described, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2014]
OrthologsView orthologs and multiple alignments for VAMP1

Proteins

vesicle-associated membrane protein 1 isoform 1
Refseq ID:NP_055046
Protein GI:7657673
UniProt ID:P23763
mRNA ID:NM_014231
Length:118
RefSeq Status:
MSAPAQPPAEGTEGTAPGGGPPGPPPNMTSNRRLQQTQAQVEEVVDIIRVNVDKVLERDQKLSELDDRADALQAGASQFESSAAKLKRKYWWKNCKMMIM
LGAICAIIVVVIVIYFFT
 
vesicle-associated membrane protein 1 isoform 2
Refseq ID:NP_954740
Protein GI:40549446
UniProt ID:P23763
mRNA ID:NM_199245
Length:117
RefSeq Status:
MSAPAQPPAEGTEGTAPGGGPPGPPPNMTSNRRLQQTQAQVEEVVDIIRVNVDKVLERDQKLSELDDRADALQAGASQFESSAAKLKRKYWWKNCKMMIM
LGAICAIIVVVIVSKYR
 
vesicle-associated membrane protein 1 isoform 3
Refseq ID:NP_058439
Protein GI:9257251
UniProt ID:P23763
mRNA ID:NM_016830
Length:116
RefSeq Status:
MSAPAQPPAEGTEGTAPGGGPPGPPPNMTSNRRLQQTQAQVEEVVDIIRVNVDKVLERDQKLSELDDRADALQAGASQFESSAAKLKRKYWWKNCKMMIM
LGAICAIIVVVIVRRD
 
vesicle-associated membrane protein 1 isoform 4
Refseq ID:NP_001284367
Protein GI:662033932
UniProt ID:P23763
mRNA ID:NM_001297438
Length:116
RefSeq Status:
MSAPAQPPAEGTEGTAPGGGPPGPPPNMTSNRRLQQTQAQVEEVVDIIRVNVDKVLERDQKLSELDDRADALQAGASQFESSAAKLKRKYWWKNCKMMIM
LGAICAIIVVVIVRRG
 
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