MGP Database

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MGP003061

Ontology/Pathway Information

Entrez Gene ID6890
Gene Nametransporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
Gene Symbol TAP1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005789 TAS:ReactomeCendoplasmic reticulum membrane
GO:0030176 IDA:UniProtKBCintegral component of endoplasmic reticulum membrane
GO:0016021 IDA:UniProtKBCintegral component of membrane
GO:0016020 IDA:UniProtKBCmembrane
GO:0005739 IEA:EnsemblCmitochondrion
GO:0042825 IDA:UniProtKBCTAP complex
GO:0043531 IDA:UniProtKBFADP binding
GO:0042626 IBA:GO_CentralFATPase activity, coupled to transmembrane movement of substances
GO:0005524 IDA:UniProtKBFATP binding
GO:0023029 IPI:UniProtKBFMHC class Ib protein binding
GO:0042605 NAS:UniProtKBFpeptide antigen binding
GO:0015197 IMP:UniProtKBFpeptide transporter activity
GO:0042803 ISS:UniProtKBFprotein homodimerization activity
GO:0046978 ISS:UniProtKBFTAP1 binding
GO:0046979 IPI:UniProtKBFTAP2 binding
GO:0019885 IMP:UniProtKBPantigen processing and presentation of endogenous peptide antigen via MHC class I
GO:0042590 TAS:ReactomePantigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0002479 TAS:ReactomePantigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002474 TAS:ReactomePantigen processing and presentation of peptide antigen via MHC class I
GO:0046967 IMP:UniProtKBPcytosol to ER transport
GO:0006952 IEA:EnsemblPdefense response
GO:0019060 IMP:UniProtKBPintracellular transport of viral protein in host cell
GO:0015833 IMP:UniProtKBPpeptide transport
GO:0055085 IBA:GO_CentralPtransmembrane transport
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75774Adaptive Immune System
REACT_75795Antigen Presentation: Folding, assembly and peptide loading of class I MHC
REACT_111119Antigen processing-Cross presentation
REACT_75820Class I MHC mediated antigen processing & presentation
REACT_111178ER-Phagosome pathway
REACT_6900Immune System
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