MGP Database

MGP003084

Ontology/Pathway Information

Entrez Gene ID	6928
Gene Name	HNF1 homeobox B
Gene Symbol	HNF1B
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005654	IDA:HPA	C	nucleoplasm
GO:0005634	IDA:UniProtKB	C	nucleus
GO:0005667	IEA:Ensembl	C	transcription factor complex
GO:0003677	IDA:UniProtKB	F	DNA binding
GO:0042803	IPI:UniProtKB	F	protein homodimerization activity
GO:0003705	IEA:Ensembl	F	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0003700	IDA:UniProtKB	F	sequence-specific DNA binding transcription factor activity
GO:0044212	IEA:Ensembl	F	transcription regulatory region DNA binding
GO:0009952	IEA:Ensembl	P	anterior/posterior pattern specification
GO:0048754	IEA:Ensembl	P	branching morphogenesis of an epithelial tube
GO:0048557	IEA:Ensembl	P	embryonic digestive tract morphogenesis
GO:0031018	IMP:UniProtKB	P	endocrine pancreas development
GO:0001714	IEA:Ensembl	P	endodermal cell fate specification
GO:0050673	IEA:Ensembl	P	epithelial cell proliferation
GO:0048806	IMP:UniProtKB	P	genitalia development
GO:0061017	IEA:Ensembl	P	hepatoblast differentiation
GO:0030902	IEA:Ensembl	P	hindbrain development
GO:0001826	IEA:Ensembl	P	inner cell mass cell differentiation
GO:0030073	IEA:Ensembl	P	insulin secretion
GO:0001822	IDA:UniProtKB	P	kidney development
GO:0072181	IEA:Ensembl	P	mesonephric duct formation
GO:0061296	IEA:Ensembl	P	negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis
GO:1900212	IEA:Ensembl	P	negative regulation of mesenchymal cell apoptotic process involved in metanephros development
GO:0000122	IEA:Ensembl	P	negative regulation of transcription from RNA polymerase II promoter
GO:0045893	IDA:UniProtKB	P	positive regulation of transcription, DNA-templated
GO:0060261	IDA:UniProtKB	P	positive regulation of transcription initiation from RNA polymerase II promoter
GO:0039020	IGI:UniProtKB	P	pronephric nephron tubule development
GO:0048793	IMP:UniProtKB	P	pronephros development
GO:0072095	IEA:Ensembl	P	regulation of branch elongation involved in ureteric bud branching
GO:0042663	IEA:Ensembl	P	regulation of endodermal cell fate specification
GO:0035565	IMP:UniProtKB	P	regulation of pronephros size
GO:0030111	IEA:Ensembl	P	regulation of Wnt signaling pathway
GO:0009749	IEA:Ensembl	P	response to glucose
GO:0060677	IEA:Ensembl	P	ureteric bud elongation

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_111045	Developmental Biology
REACT_13698	Regulation of beta-cell development
REACT_13778	Regulation of gene expression in early pancreatic precursor cells
REACT_13673	Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells