MGP Database

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MGP003111

Record overview

MGPD IDMGP003111
Gene ID7025
SpeciesHomo sapiens (Human)
Gene Namenuclear receptor subfamily 2, group F, member 1
Gene Symbol NR2F1
SynonymsEAR3; BBOAS; EAR-3; NR2F2; SVP44; BBSOAS; ERBAL3; TFCOUP1; COUP-TFI; TCFCOUP1;
Alternate namesCOUP transcription factor 1; COUP transcription factor I; COUP-TF I; COUP-TF1; V-erbA-related protein 3; chicken ovalbumin upstream promoter-transcription factor I; transcription factor COUP 1 (chicken ovalbumin upstream promoter 1, v-erb-a homolog-like 3);
Chromosome5
Map Location5q14
SummaryThe protein encoded by this gene is a nuclear hormone receptor and transcriptional regulator. The encoded protein acts as a homodimer and binds to 5'-AGGTCA-3' repeats. Defects in this gene are a cause of Bosch-Boonstra optic atrophy syndrome (BBOAS). [provided by RefSeq, Apr 2014]
OrthologsView orthologs and multiple alignments for NR2F1

Proteins

COUP transcription factor 1
Refseq ID:NP_005645
Protein GI:5032173
UniProt ID:P10589
mRNA ID:NM_005654
Length:423
RefSeq Status:
MAMVVSSWRDPQDDVAGGNPGGPNPAAQAARGGGGGAGEQQQQAGSGAPHTPQTPGQPGAPATPGTAGDKGQGPPGSGQSQQHIECVVCGDKSSGKHYGQ
FTCEGCKSFFKRSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPNPGQYALTNGDPLNGHCYLSGYISLLLRAEPYPT
SRYGSQCMQPNNIMGIENICELAARLLFSAVEWARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIR
IFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQEKSQCALEEYVRSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIE
TLIRDMLLSGSSFNWPYMSIQCS
 
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