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MGP Database

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MGP003127

Ontology/Pathway Information

Entrez Gene ID	7056
Gene Name	thrombomodulin
Gene Symbol	THBD
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0009986	IDA:BHF-UCL	C	cell surface
GO:0005615	IEA:Ensembl	C	extracellular space
GO:0005887	TAS:ProtInc	C	integral component of plasma membrane
GO:0005886	TAS:Reactome	C	plasma membrane
GO:0005509	TAS:ProtInc	F	calcium ion binding
GO:0030246	IEA:InterPro	F	carbohydrate binding
GO:0004872	TAS:ProtInc	F	receptor activity
GO:0004888	IEA:InterPro	F	transmembrane signaling receptor activity
GO:0007596	TAS:Reactome	P	blood coagulation
GO:0007565	IEA:Ensembl	P	female pregnancy
GO:0050900	TAS:Reactome	P	leukocyte migration
GO:0030195	TAS:BHF-UCL	P	negative regulation of blood coagulation
GO:0051918	TAS:BHF-UCL	P	negative regulation of fibrinolysis
GO:0010544	TAS:BHF-UCL	P	negative regulation of platelet activation
GO:0051591	IEA:Ensembl	P	response to cAMP
GO:0032496	IEA:Ensembl	P	response to lipopolysaccharide
GO:0010165	IEA:Ensembl	P	response to X-ray

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_12051	Cell surface interactions at the vascular wall
REACT_1439	Common Pathway
REACT_2051	Formation of Fibrin Clot (Clotting Cascade)
REACT_604	Hemostasis