MGP Database

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MGP003171

Ontology/Pathway Information

Entrez Gene ID7150
Gene Nametopoisomerase (DNA) I
Gene Symbol TOP1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0000932 IDA:UniProtKBCcytoplasmic mRNA processing body
GO:0005730 IDA:UniProtKBCnucleolus
GO:0005654 IDA:UniProtKBCnucleoplasm
GO:0005634 IDA:UniProtKBCnucleus
GO:0043204 IEA:EnsemblCperikaryon
GO:0031298 IBA:GO_CentralCreplication fork protection complex
GO:0003682 IDA:UniProtKBFchromatin binding
GO:0001046 IDA:UniProtKBFcore promoter sequence-specific DNA binding
GO:0003677 IDA:UniProtKBFDNA binding
GO:0003917 IDA:UniProtKBFDNA topoisomerase type I activity
GO:0003918 IEA:InterProFDNA topoisomerase type II (ATP-hydrolyzing) activity
GO:0044822 IDA:UniProtKBFpoly(A) RNA binding
GO:0006338 IMP:UniProtKBPchromatin remodeling
GO:0007059 IBA:GO_CentralPchromosome segregation
GO:0032922 IMP:UniProtKBPcircadian regulation of gene expression
GO:0007623 IEP:UniProtKBPcircadian rhythm
GO:0006260 IBA:GO_CentralPDNA replication
GO:0006265 IDA:UniProtKBPDNA topological change
GO:0040016 IEA:EnsemblPembryonic cleavage
GO:0016310 NAS:UniProtKBPphosphorylation
GO:0012501 NAS:UniProtKBPprogrammed cell death
GO:0042493 IEP:UniProtKBPresponse to drug
GO:0016032 IEA:UniProtKB-KWPviral process
SMP Pathway Links
SMP IDDescription
SMP00433Irinotecan Action Pathway
SMP00600Irinotecan Metabolism Pathway
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