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MGP003178

Record overview

MGPD IDMGP003178
Gene ID7164
SpeciesHomo sapiens (Human)
Gene Nametumor protein D52-like 1
Gene Symbol TPD52L1
SynonymsD53; hD53;
Alternate namestumor protein D53;
Chromosome6
Map Location6q22-q23
SummaryThis gene encodes a member of the tumor protein D52 (TPD52) family. The encoded protein contains a coiled-coil domain and may form homo- or hetero-dimer with TPD52 family members. The protein is reported to be involved in cell proliferation and calcium signaling. It also interacts with the mitogen-activated protein kinase kinase kinase 5 (MAP3K5/ASK1) and positively regulates MAP3K5-induced apoptosis. Multiple alternatively spliced transcript variants have been observed, but the full-length nature of some variants has not yet been determined. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for TPD52L1

Proteins

tumor protein D53 isoform 1
Refseq ID:NP_003278
Protein GI:4507641
UniProt ID:Q16890
mRNA ID:NM_003287
Length:204
RefSeq Status:
MEAQAQGLLETEPLQGTDEDAVASADFSSMLSEEEKEELKAELVQLEDEITTLRQVLSAKERHLVEIKQKLGMNLMNELKQNFSKSWHDMQTTTAYKKTH
ETLSHAGQKATAAFSNVGTAISKKFGDMSYSIRHSISMPAMRNSPTFKSFEERVETTVTSLKTKVGGTNPNGGSFEEVLSSTAHASAQSLAGGSRRTKEE
ELQC
 
tumor protein D53 isoform 2
Refseq ID:NP_001003395
Protein GI:51173744
UniProt ID:Q16890
mRNA ID:NM_001003395
Length:175
RefSeq Status:
MLSEEEKEELKAELVQLEDEITTLRQVLSAKERHLVEIKQKLGMNLMNELKQNFSKSWHDMQTTTAYKKTHETLSHAGQKATAAFSNVGTAISKKFGDMS
YSIRHSISMPAMRNSPTFKSFEERVETTVTSLKTKVGGTNPNGGSFEEVLSSTAHASAQSLAGGSRRTKEEELQC
 
tumor protein D53 isoform 3
Refseq ID:NP_001003396
Protein GI:51173746
UniProt ID:Q16890
mRNA ID:NM_001003396
Length:144
RefSeq Status:
MEAQAQGLLETEPLQGTDEDAVASADFSSMLSEEEKEELKAELVQLEDEITTLRQVLSAKERHLVEIKQKLGMNLMNELKQNFSKSWHDMQTTTAYKKTH
ETLSHAGQKATAAFSNVGTAISKKFGDMSYSIRHSISMPAMRRK
 
tumor protein D53 isoform 4
Refseq ID:NP_001003397
Protein GI:51173748
UniProt ID:Q16890
mRNA ID:NM_001003397
Length:131
RefSeq Status:
MEAQAQGLLETEPLQGTDEDAVASADFSSMLSEEEKEELKAELVQLEDEITTLRQVLSAKERHLVEIKQKLGMNLMNELKQNFSKSWHDMQTTTAYKKTH
ETLSHAGQKATAAFSNVGTAISKKFGDMRRK
 
tumor protein D53 isoform 5
Refseq ID:NP_001278955
Protein GI:635372934
UniProt ID:Q16890
mRNA ID:NM_001292026
Length:102
RefSeq Status:
MLSEEEKEELKAELVQLEDEITTLRQVLSAKERHLVEIKQKLGMNLMNELKQNFSKSWHDMQTTTAYKKTHETLSHAGQKATAAFSNVGTAISKKFGDMR
RK
 
tumor protein D53 isoform 6
Refseq ID:NP_001287923
Protein GI:665821144
UniProt ID:Q16890
mRNA ID:NM_001300994
Length:191
RefSeq Status:
MEAQAQGLLETEPLQGTDEDAVASADFSSMLSEEEKEELKAELVQLEDEITTLRQVLSAKERHLVEIKQKLGMNLMNELKQNFSKSWHDMQTTTAYKKTH
ETLSHAGQKATAAFSNVGTAISKKFGDMRNSPTFKSFEERVETTVTSLKTKVGGTNPNGGSFEEVLSSTAHASAQSLAGGSRRTKEEELQC
 
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