MGP Database

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MGP003186

Ontology/Pathway Information

Entrez Gene ID7173
Gene Namethyroid peroxidase
Gene Symbol TPO
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0009986 IEA:UniProtKB-SubCellCcell surface
GO:0005615 IDA:UniProtKBCextracellular space
GO:0005887 TAS:ProtIncCintegral component of plasma membrane
GO:0005739 IEA:EnsemblCmitochondrion
GO:0005886 TAS:ReactomeCplasma membrane
GO:0005509 IEA:InterProFcalcium ion binding
GO:0020037 IEA:InterProFheme binding
GO:0004447 IEA:UniProtKB-ECFiodide peroxidase activity
GO:0004601 TAS:ProtIncFperoxidase activity
GO:0034641 TAS:ReactomePcellular nitrogen compound metabolic process
GO:0035162 IDA:DFLATPembryonic hemopoiesis
GO:0042446 IEA:UniProtKB-KWPhormone biosynthetic process
GO:0042744 IEA:UniProtKB-KWPhydrogen peroxide catabolic process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0006590 TAS:ReactomePthyroid hormone generation
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_15513Amine-derived hormones
REACT_111217Metabolism
REACT_13Metabolism of amino acids and derivatives
REACT_15292Thyroxine biosynthesis
SMP Pathway Links
SMP IDDescription
SMP00716Thyroid hormone synthesis
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