MGP Database

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MGP003227

Ontology/Pathway Information

Entrez Gene ID7296
Gene Namethioredoxin reductase 1
Gene Symbol TXNRD1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 TAS:ReactomeCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005739 IEA:EnsemblCmitochondrion
GO:0005730 IDA:HPACnucleolus
GO:0005654 IDA:HPACnucleoplasm
GO:0009055 IEA:InterProFelectron carrier activity
GO:0050660 IEA:InterProFflavin adenine dinucleotide binding
GO:0050661 IEA:InterProFNADP binding
GO:0015035 IEA:InterProFprotein disulfide oxidoreductase activity
GO:0004791 EXP:ReactomeFthioredoxin-disulfide reductase activity
GO:0008283 IEA:EnsemblPcell proliferation
GO:0045454 IEA:InterProPcell redox homeostasis
GO:0044255 TAS:ReactomePcellular lipid metabolic process
GO:0001707 IEA:EnsemblPmesoderm formation
GO:0015949 TAS:ReactomePnucleobase-containing small molecule interconversion
GO:0055086 TAS:ReactomePnucleobase-containing small molecule metabolic process
GO:0007165 NAS:ProtIncPsignal transduction
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_120956Cellular responses to stress
REACT_264249Detoxification of Reactive Oxygen Species
REACT_116125Disease
REACT_22279Fatty acid, triacylglycerol, and ketone body metabolism
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_1698Metabolism of nucleotides
REACT_116145PPARA activates gene expression
REACT_19241Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
REACT_21330Synthesis and interconversion of nucleotide di- and triphosphates
REACT_264041Uptake and actions of bacterial toxins
REACT_268571Uptake and function of diphtheria toxin
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