MGP Database

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MGP003289

Ontology/Pathway Information

Entrez Gene ID7414
Gene Namevinculin
Gene Symbol VCL
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0015629 IEA:InterProCactin cytoskeleton
GO:0005912 ISS:UniProtKBCadherens junction
GO:0005913 IDA:BHF-UCLCcell-cell adherens junction
GO:0005911 ISS:UniProtKBCcell-cell junction
GO:0030055 NAS:UniProtKBCcell-substrate junction
GO:0043034 ISS:UniProtKBCcostamere
GO:0005856 TAS:UniProtKBCcytoskeleton
GO:0005829 TAS:ReactomeCcytosol
GO:0005576 TAS:ReactomeCextracellular region
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005916 IEA:EnsemblCfascia adherens
GO:0005925 IDA:UniProtKBCfocal adhesion
GO:0005886 IEA:UniProtKB-SubCellCplasma membrane
GO:0043234 IDA:UniProtKBCprotein complex
GO:0031982 IDA:UniProtKBCvesicle
GO:0003779 IDA:BHF-UCLFactin binding
GO:0045294 IPI:UniProtKBFalpha-catenin binding
GO:0008013 ISS:BHF-UCLFbeta-catenin binding
GO:0045296 ISS:BHF-UCLFcadherin binding
GO:0002162 IPI:UniProtKBFdystroglycan binding
GO:0005198 IEA:InterProFstructural molecule activity
GO:0034333 IMP:BHF-UCLPadherens junction assembly
GO:0043297 IMP:UniProtKBPapical junction assembly
GO:0007596 TAS:ReactomePblood coagulation
GO:0007155 TAS:UniProtKBPcell adhesion
GO:0007160 TAS:BHF-UCLPcell-matrix adhesion
GO:0006928 TAS:UniProtKBPcellular component movement
GO:0090136 IMP:BHF-UCLPepithelial cell-cell adhesion
GO:0030032 ISS:UniProtKBPlamellipodium assembly
GO:0002009 IMP:BHF-UCLPmorphogenesis of an epithelium
GO:0006936 TAS:ReactomePmuscle contraction
GO:0030336 TAS:UniProtKBPnegative regulation of cell migration
GO:0030168 TAS:ReactomePplatelet activation
GO:0070527 IMP:UniProtKBPplatelet aggregation
GO:0002576 TAS:ReactomePplatelet degranulation
GO:0034394 IMP:BHF-UCLPprotein localization to cell surface
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_604Hemostasis
REACT_17044Muscle contraction
REACT_798Platelet activation, signaling and aggregation
REACT_318Platelet degranulation
REACT_1280Response to elevated platelet cytosolic Ca2+
REACT_20558Smooth Muscle Contraction
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