MGP Database

MGP003312

Ontology/Pathway Information

Entrez Gene ID7465
Gene NameWEE1 G2 checkpoint kinase
Gene Symbol WEE1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IEA:EnsemblCcytoplasm
GO:0005654 TAS:ReactomeCnucleoplasm
GO:0005634 TAS:ProtIncCnucleus
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0000287 IEA:InterProFmagnesium ion binding
GO:0004715 IEA:UniProtKB-ECFnon-membrane spanning protein tyrosine kinase activity
GO:0004674 IEA:InterProFprotein serine/threonine kinase activity
GO:0004713 TAS:ProtIncFprotein tyrosine kinase activity
GO:0007596 TAS:ReactomePblood coagulation
GO:0051301 IEA:UniProtKB-KWPcell division
GO:0030010 IEA:EnsemblPestablishment of cell polarity
GO:0000082 TAS:ReactomePG1/S transition of mitotic cell cycle
GO:0000086 TAS:ReactomePG2/M transition of mitotic cell cycle
GO:0000226 IEA:EnsemblPmicrotubule cytoskeleton organization
GO:0000278 TAS:ReactomePmitotic cell cycle
GO:0007067 IEA:UniProtKB-KWPmitotic nuclear division
GO:0048812 IEA:EnsemblPneuron projection morphogenesis
GO:0051726 TAS:ReactomePregulation of cell cycle
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_115566Cell Cycle
REACT_1538Cell Cycle Checkpoints
REACT_152Cell Cycle, Mitotic
REACT_407Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
REACT_1857Cyclin A/B1 associated events during G2/M transition
REACT_9029Cyclin A:Cdk2-associated events at S phase entry
REACT_1574Cyclin E associated events during G1/S transition
REACT_24970Factors involved in megakaryocyte development and platelet production
REACT_1783G1/S Transition
REACT_828G2/M Checkpoints
REACT_897G2/M DNA damage checkpoint
REACT_1846G2/M DNA replication checkpoint
REACT_2203G2/M Transition
REACT_604Hemostasis
REACT_21267Mitotic G1-G1/S phases
REACT_21391Mitotic G2-G2/M phases
REACT_1006Polo-like kinase mediated events
REACT_899S Phase
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