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MGP003381

Record overview

MGPD IDMGP003381
Gene ID7704
SpeciesHomo sapiens (Human)
Gene Namezinc finger and BTB domain containing 16
Gene Symbol ZBTB16
SynonymsPLZF; ZNF145;
Alternate nameszinc finger and BTB domain-containing protein 16; promyelocytic leukaemia zinc finger; zinc finger protein 145 (Kruppel-like, expressed in promyelocytic leukemia); zinc finger protein PLZF;
Chromosome11
Map Location11q23.1
SummaryThis gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for ZBTB16

Proteins

zinc finger and BTB domain-containing protein 16
Refseq ID:NP_005997
Protein GI:21359888
UniProt ID:Q05516
mRNA ID:NM_006006
Length:673
RefSeq Status:
MDLTKMGMIQLQNPSHPTGLLCKANQMRLAGTLCDVVIMVDSQEFHAHRTVLACTSKMFEILFHRNSQHYTLDFLSPKTFQQILEYAYTATLQAKAEDLD
DLLYAAEILEIEYLEEQCLKMLETIQASDDNDTEATMADGGAEEEEDRKARYLKNIFISKHSSEESGYASVAGQSLPGPMVDQSPSVSTSFGLSAMSPTK
AAVDSLMTIGQSLLQGTLQPPAGPEEPTLAGGGRHPGVAEVKTEMMQVDEVPSQDSPGAAESSISGGMGDKVEERGKEGPGTPTRSSVITSARELHYGRE
ESAEQVPPPAEAGQAPTGRPEHPAPPPEKHLGIYSVLPNHKADAVLSMPSSVTSGLHVQPALAVSMDFSTYGGLLPQGFIQRELFSKLGELAVGMKSESR
TIGEQCSVCGVELPDNEAVEQHRKLHSGMKTYGCELCGKRFLDSLRLRMHLLAHSAGAKAFVCDQCGAQFSKEDALETHRQTHTGTDMAVFCLLCGKRFQ
AQSALQQHMEVHAGVRSYICSECNRTFPSHTALKRHLRSHTGDHPYECEFCGSCFRDESTLKSHKRIHTGEKPYECNGCGKKFSLKHQLETHYRVHTGEK
PFECKLCHQRSRDYSAMIKHLRTHNGASPYQCTICTEYCPSLSSMQKHMKGHKPEEIPPDWRIEKTYLYLCYV
 
zinc finger and BTB domain-containing protein 16
Refseq ID:NP_001018011
Protein GI:66932932
UniProt ID:Q05516
mRNA ID:NM_001018011
Length:673
RefSeq Status:
Protein sequence is identical to GI:21359888 (mRNA isoform)
 
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