MGP Database

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MGP003428

Ontology/Pathway Information

Entrez Gene ID7915
Gene Namealdehyde dehydrogenase 5 family, member A1
Gene Symbol ALDH5A1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005759 TAS:ReactomeCmitochondrial matrix
GO:0005739 IDA:UniProtKBCmitochondrion
GO:0004029 IBA:GO_CentralFaldehyde dehydrogenase (NAD) activity
GO:0042803 IC:UniProtKBFprotein homodimerization activity
GO:0004777 IDA:UniProtKBFsuccinate-semialdehyde dehydrogenase (NAD+) activity
GO:0009013 IBA:GO_CentralFsuccinate-semialdehyde dehydrogenase [NAD(P)+] activity
GO:0006083 ISS:UniProtKBPacetate metabolic process
GO:0007417 IMP:UniProtKBPcentral nervous system development
GO:0006681 ISS:UniProtKBPgalactosylceramide metabolic process
GO:0009450 IDA:UniProtKBPgamma-aminobutyric acid catabolic process
GO:0006006 ISS:UniProtKBPglucose metabolic process
GO:0006678 IEA:EnsemblPglucosylceramide metabolic process
GO:0006536 ISS:UniProtKBPglutamate metabolic process
GO:0006541 ISS:UniProtKBPglutamine metabolic process
GO:0006749 ISS:UniProtKBPglutathione metabolic process
GO:0006650 ISS:UniProtKBPglycerophospholipid metabolic process
GO:0042135 ISS:UniProtKBPneurotransmitter catabolic process
GO:0007269 TAS:ReactomePneurotransmitter secretion
GO:0009791 IEA:EnsemblPpost-embryonic development
GO:0051289 IDA:UniProtKBPprotein homotetramerization
GO:0022904 ISS:UniProtKBPrespiratory electron transport chain
GO:0046459 ISS:UniProtKBPshort-chain fatty acid metabolic process
GO:0006105 ISS:UniProtKBPsuccinate metabolic process
GO:0007268 TAS:ReactomePsynaptic transmission
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_23964Degradation of GABA
REACT_23947GABA synthesis, release, reuptake and degradation
REACT_13685Neuronal System
REACT_13723Neurotransmitter Release Cycle
REACT_13477Transmission across Chemical Synapses
SMP Pathway Links
SMP IDDescription
SMP001362-Hydroxyglutric Aciduria (D And L Form)
SMP002434-Hydroxybutyric Aciduria/Succinic Semialdehyde Dehydrogenase Deficiency
SMP00072Glutamate Metabolism
SMP00385Homocarnosinosis
SMP00339Hyperinsulinism-Hyperammonemia Syndrome
SMP00567Succinic semialdehyde dehydrogenase deficiency
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