MGP Database

MGP003450

Record overview

MGPD ID	MGP003450
Gene ID	8076
Species	Homo sapiens (Human)
Gene Name	microfibrillar associated protein 5
Gene Symbol	MFAP5
Synonyms	AAT9; MP25; MAGP2; MAGP-2; MFAP-5;
Alternate names	microfibrillar-associated protein 5; microfibril-associated glycoprotein-2;
Chromosome	12
Map Location	12p13.1-p12.3
Summary	This gene encodes a 25-kD microfibril-associated glycoprotein which is a component of microfibrils of the extracellular matrix. The encoded protein promotes attachment of cells to microfibrils via alpha-V-beta-3 integrin. Deficiency of this gene in mice results in neutropenia. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
Orthologs	View orthologs and multiple alignments for MFAP5

Proteins

microfibrillar-associated protein 5 isoform a precursor

Refseq ID:	NP_003471
Protein GI:	4505089
UniProt ID:	Q13361
mRNA ID:	NM_003480
Length:	173
RefSeq Status:

`MSLLGPKVLLFLAAFIITSDWIPLGVNSQRGDDVTQATPETFTEDPNLVNDPATDETVLAVLADIAPSTDDLASLSEKNTTAECWDEKFTCTRLYSVHRP VKQCIHQLCFTSLRRMYIVNKEICSRLVCKEHEAMKDELCRQMAGLPPRRLRRSNYFRLPPCENVDLQRPNGL`

microfibrillar-associated protein 5 isoform b precursor
`sig_peptide: 1..28 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 3017 peptide sequence: MSLLGPKVLLFLAAFIITSDWIPLGVNS`

Refseq ID:	NP_001284638
Protein GI:	663071064
UniProt ID:	Q13361
mRNA ID:	NM_001297709
Length:	163
RefSeq Status:

`MSLLGPKVLLFLAAFIITSDWIPLGVNSQRGDDVTQATPETFTEDPNLVNDPATDETVLAVLADIAPSTDDLECWDEKFTCTRLYSVHRPVKQCIHQLCF TSLRRMYIVNKEICSRLVCKEHEAMKDELCRQMAGLPPRRLRRSNYFRLPPCENVDLQRPNGL`

sig_peptide: 1..28
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 3017
peptide sequence: 
MSLLGPKVLLFLAAFIITSDWIPLGVNS

sig_peptide: 1..28
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 3017
peptide sequence: 
MSLLGPKVLLFLAAFIITSDWIPLGVNS

sig_peptide: 1..28
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 3017
peptide sequence: 
MSLLGPKVLLFLAAFIITSDWIPLGVNS

sig_peptide: 1..25
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2664
peptide sequence: 
MSLLGPKVLLFLAAFIITSDDVTQA

sig_peptide: 1..28
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 3017
peptide sequence: 
MSLLGPKVLLFLAAFIITSDWIPLGVNS

microfibrillar-associated protein 5 isoform c precursor

Refseq ID:	NP_001284639
Protein GI:	663071066
UniProt ID:	B3KW70
mRNA ID:	NM_001297710
Length:	151
RefSeq Status:

`MSLLGPKVLLFLAAFIITSDDVTQATPETFTEDPNLVNDPATDETVLAVLADIAPSTDDLECWDEKFTCTRLYSVHRPVKQCIHQLCFTSLRRMYIVNKE ICSRLVCKEHEAMKDELCRQMAGLPPRRLRRSNYFRLPPCENVDLQRPNGL`

sig_peptide: 1..28
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 3017
peptide sequence: 
MSLLGPKVLLFLAAFIITSDWIPLGVNS

sig_peptide: 1..28
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 3017
peptide sequence: 
MSLLGPKVLLFLAAFIITSDWIPLGVNS

sig_peptide: 1..28
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 3017
peptide sequence: 
MSLLGPKVLLFLAAFIITSDWIPLGVNS

sig_peptide: 1..25
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2664
peptide sequence: 
MSLLGPKVLLFLAAFIITSDDVTQA

microfibrillar-associated protein 5 isoform d precursor

Refseq ID:	NP_001284640
Protein GI:	663071068
UniProt ID:	B3KW70
mRNA ID:	NM_001297711
Length:	148
RefSeq Status:

`MSLLGPKVLLFLAAFIITSDWIPLGVNSQRGDDVTQATPETFTEDPNLVNDPATDETECWDEKFTCTRLYSVHRPVKQCIHQLCFTSLRRMYIVNKEICS RLVCKEHEAMKDELCRQMAGLPPRRLRRSNYFRLPPCENVDLQRPNGL`

sig_peptide: 1..28
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 3017
peptide sequence: 
MSLLGPKVLLFLAAFIITSDWIPLGVNS

sig_peptide: 1..28
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 3017
peptide sequence: 
MSLLGPKVLLFLAAFIITSDWIPLGVNS

sig_peptide: 1..28
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 3017
peptide sequence: 
MSLLGPKVLLFLAAFIITSDWIPLGVNS

microfibrillar-associated protein 5 isoform e precursor

Refseq ID:	NP_001284641
Protein GI:	663071070
UniProt ID:	B3KW70
mRNA ID:	NM_001297712
Length:	109
RefSeq Status:

`MSLLGPKVLLFLAAFIITSDWIPLGVNSQRGDDVTQATPETFTEDPNLVNDPATDETVLAVLADIAPSTDDLDELCRQMAGLPPRRLRRSNYFRLPPCEN VDLQRPNGL`

sig_peptide: 1..28
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 3017
peptide sequence: 
MSLLGPKVLLFLAAFIITSDWIPLGVNS

sig_peptide: 1..28
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 3017
peptide sequence: 
MSLLGPKVLLFLAAFIITSDWIPLGVNS