MGP Database

MGP003461

Ontology/Pathway Information

Entrez Gene ID8140
Gene Namesolute carrier family 7 (amino acid transporter light chain, L system), member 5
Gene Symbol SLC7A5
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0016324 IEA:UniProtKB-SubCellCapical plasma membrane
GO:0005737 IDA:HPACcytoplasm
GO:0005829 IEA:UniProtKB-SubCellCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0016021 IEA:UniProtKB-KWCintegral component of membrane
GO:0043231 IDA:HPACintracellular membrane-bounded organelle
GO:0016020 IDA:UniProtKBCmembrane
GO:0005730 IDA:HPACnucleolus
GO:0005634 IDA:HPACnucleus
GO:0005886 IDA:HPACplasma membrane
GO:0015171 ISS:UniProtKBFamino acid transmembrane transporter activity
GO:0015179 IEA:EnsemblFL-amino acid transmembrane transporter activity
GO:0015175 TAS:ProtIncFneutral amino acid transmembrane transporter activity
GO:0042605 ISS:UniProtKBFpeptide antigen binding
GO:0006865 TAS:ReactomePamino acid transport
GO:0007596 TAS:ReactomePblood coagulation
GO:0030154 IEA:UniProtKB-KWPcell differentiation
GO:0006520 TAS:ProtIncPcellular amino acid metabolic process
GO:0006811 TAS:ReactomePion transport
GO:0050900 TAS:ReactomePleukocyte migration
GO:0007399 IEA:UniProtKB-KWPnervous system development
GO:0015804 ISS:UniProtKBPneutral amino acid transport
GO:0055085 TAS:ReactomePtransmembrane transport
GO:0006810 TAS:ProtIncPtransport
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_13796Amino acid transport across the plasma membrane
REACT_12560Basigin interactions
REACT_12051Cell surface interactions at the vascular wall
REACT_604Hemostasis
REACT_19118SLC-mediated transmembrane transport
REACT_15518Transmembrane transport of small molecules
REACT_19397Transport of inorganic cations/anions and amino acids/oligopeptides
SMP Pathway Links
SMP IDDescription
SMP00133Amiloride Action Pathway
SMP00090Bendroflumethiazide Action Pathway
SMP00583Blue diaper syndrome
SMP00088Bumetanide Action Pathway
SMP00078Chlorothiazide Action Pathway
SMP00122Chlorthalidone Action Pathway
SMP00103Cyclothiazide Action Pathway
SMP00723Cystinuria
SMP00135Eplerenone Action Pathway
SMP00097Ethacrynic Acid Action Pathway
SMP00115Furosemide Action Pathway
SMP00245Glucose Transporter Defect (SGLT2)
SMP00189Hartnup Disorder
SMP00100Hydrochlorothiazide Action Pathway
SMP00108Hydroflumethiazide Action Pathway
SMP00193Iminoglycinuria
SMP00584Iminoglycinuria
SMP00110Indapamide Action Pathway
SMP00483Kidney Function
SMP00682Leucine Stimulation on Insulin Signaling
SMP00197Lysinuric Protein Intolerance
SMP00585Lysinuric protein intolerance (LPI)
SMP00081Methyclothiazide Action Pathway
SMP00105Metolazone Action Pathway
SMP00080Polythiazide Action Pathway
SMP00091Quinethazone Action Pathway
SMP00184Renal Glucosuria
SMP00134Spironolactone Action Pathway
SMP00118Torsemide Action Pathway
SMP00132Triamterene Action Pathway
SMP00121Trichlormethiazide Action Pathway
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