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MGP003470

Record overview

MGPD IDMGP003470
Gene ID8228
SpeciesHomo sapiens (Human)
Gene Namepatatin-like phospholipase domain containing 4
Gene Symbol PNPLA4
SynonymsGS2; DXS1283E; iPLA2eta;
Alternate namespatatin-like phospholipase domain-containing protein 4; IPLA2 eta; calcium independent phospholipases A2 eta;
ChromosomeX
Map LocationXp22.3
EC Number3.1.1.3
SummaryThis gene encodes a member of the patatin-like family of phospholipases. The encoded enzyme has both triacylglycerol lipase and transacylase activities and may be involved in adipocyte triglyceride homeostasis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome Y. [provided by RefSeq, Feb 2010]
OrthologsView orthologs and multiple alignments for PNPLA4

Proteins

patatin-like phospholipase domain-containing protein 4 isoform 1 precursor
Refseq ID:NP_001135861
Protein GI:215422355
UniProt ID:P41247
mRNA ID:NM_001142389
Length:253
RefSeq Status:
MKHINLSFAACGFLGIYHLGAASALCRHGKKLVKDVKAFAGASAGSLVASVLLTAPEKIEECNQFTYKFAEEIRRQSFGAVTPGYDFMARLRSGMESILP
PSAHELAQNRLHVSITNAKTRENHLVSTFSSREDLIKVLLASSFVPIYAGLKLVEYKGQKWVDGGLTNALPILPVGRTVTISPFSGRLDISPQDKGQLDL
YVNIAKQDIMLSLANLVRLNQALFPPSKRKMESLYQCGFDDTVKFLLKENWFE
 
sig_peptide: 1..24
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2493
peptide sequence: 
MKHINLSFAACGFLGIYHLGAASA

sig_peptide: 1..24
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2493
peptide sequence: 
MKHINLSFAACGFLGIYHLGAASA
 
patatin-like phospholipase domain-containing protein 4 isoform 1 precursor
Refseq ID:NP_004641
Protein GI:42415471
UniProt ID:P41247
mRNA ID:NM_004650
Length:253
RefSeq Status:
Protein sequence is identical to GI:215422355 (mRNA isoform)
 
sig_peptide: 1..24
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2493
peptide sequence: 
MKHINLSFAACGFLGIYHLGAASA
 
patatin-like phospholipase domain-containing protein 4 isoform 2
Refseq ID:NP_001166143
Protein GI:291045302
UniProt ID:P41247
mRNA ID:NM_001172672
Length:166
RefSeq Status:
MARLRSGMESILPPSAHELAQNRLHVSITNAKTRENHLVSTFSSREDLIKVLLASSFVPIYAGLKLVEYKGQKWVDGGLTNALPILPVGRTVTISPFSGR
LDISPQDKGQLDLYVNIAKQDIMLSLANLVRLNQALFPPSKRKMESLYQCGFDDTVKFLLKENWFE
 
sig_peptide: 1..24
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2493
peptide sequence: 
MKHINLSFAACGFLGIYHLGAASA

sig_peptide: 1..24
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2493
peptide sequence: 
MKHINLSFAACGFLGIYHLGAASA
 
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