MGP Database

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MGP003473

Ontology/Pathway Information

Entrez Gene ID8243
Gene Namestructural maintenance of chromosomes 1A
Gene Symbol SMC1A
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005694 TAS:ReactomeCchromosome
GO:0000775 TAS:ReactomeCchromosome, centromeric region
GO:0008280 TAS:UniProtKBCcohesin core heterodimer
GO:0000777 IEA:UniProtKB-SubCellCcondensed chromosome kinetochore
GO:0000794 TAS:ProtIncCcondensed nuclear chromosome
GO:0005737 IDA:HPACcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0000776 IDA:UniProtKBCkinetochore
GO:0030893 IDA:UniProtKBCmeiotic cohesin complex
GO:0005730 IDA:HPACnucleolus
GO:0005654 IDA:HPACnucleoplasm
GO:0005634 IDA:UniProtKBCnucleus
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0003682 IDA:UniProtKBFchromatin binding
GO:0003777 NAS:UniProtKBFmicrotubule motor activity
GO:0044822 IDA:UniProtKBFpoly(A) RNA binding
GO:0046982 IPI:UniProtKBFprotein heterodimerization activity
GO:0051301 IEA:UniProtKB-KWPcell division
GO:0006281 TAS:UniProtKBPDNA repair
GO:0010467 TAS:ReactomePgene expression
GO:0007126 ISS:UniProtKBPmeiotic nuclear division
GO:0000278 TAS:ReactomePmitotic cell cycle
GO:0007093 IDA:UniProtKBPmitotic cell cycle checkpoint
GO:0007064 TAS:UniProtKBPmitotic sister chromatid cohesion
GO:0000070 TAS:UniProtKBPmitotic sister chromatid segregation
GO:0007052 TAS:UniProtKBPmitotic spindle organization
GO:0000398 TAS:ReactomePmRNA splicing, via spliceosome
GO:0032876 IMP:BHF-UCLPnegative regulation of DNA endoreduplication
GO:0009314 IEP:UniProtKBPresponse to radiation
GO:0008380 TAS:ReactomePRNA splicing
GO:0042770 IDA:UniProtKBPsignal transduction in response to DNA damage
GO:0007062 IMP:BHF-UCLPsister chromatid cohesion
GO:0019827 IEA:EnsemblPstem cell maintenance
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_115566Cell Cycle
REACT_152Cell Cycle, Mitotic
REACT_150421Cohesin Loading onto Chromatin
REACT_150266Establishment of Sister Chromatid Cohesion
REACT_71Gene Expression
REACT_111183Meiosis
REACT_75792Meiotic synapsis
REACT_1275Mitotic Anaphase
REACT_150314Mitotic Metaphase and Anaphase
REACT_682Mitotic Prometaphase
REACT_1932Mitotic Telophase/Cytokinesis
REACT_910M Phase
REACT_1735mRNA Splicing
REACT_467mRNA Splicing - Major Pathway
REACT_125Processing of Capped Intron-Containing Pre-mRNA
REACT_150425Resolution of Sister Chromatid Cohesion
REACT_150471Separation of Sister Chromatids
REACT_899S Phase
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