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MGP003564

UniProt Annotations

Entry Information
Gene NameG protein-coupled receptor 65
Protein EntryPSYR_HUMAN
UniProt IDQ8IYL9
SpeciesHuman
Comments
Comment typeDescription
FunctionReceptor for the glycosphingolipid psychosine (PSY) and several related glycosphingolipids. May have a role in activation- induced cell death or differentiation of T-cells. {ECO:0000269|PubMed:11309421}.
SimilarityBelongs to the G-protein coupled receptor 1 family. {ECO:0000255|PROSITE-ProRule:PRU00521}.
Subcellular LocationCell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Tissue SpecificityPredominantly expressed in thymus, spleen, lymph nodes, small intestine, lung, placenta and peripheral blood leukocytes. {ECO:0000269|PubMed:11309421, ECO:0000269|PubMed:9655242}.
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