MGP Database

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MGP003581

Ontology/Pathway Information

Entrez Gene ID8519
Gene Nameinterferon induced transmembrane protein 1
Gene Symbol IFITM1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0016021 IEA:UniProtKB-KWCintegral component of membrane
GO:0016020 IDA:UniProtKBCmembrane
GO:0005886 TAS:ReactomeCplasma membrane
GO:0005057 TAS:ProtIncFreceptor signaling protein activity
GO:0007166 TAS:ProtIncPcell surface receptor signaling pathway
GO:0019221 TAS:ReactomePcytokine-mediated signaling pathway
GO:0051607 IEA:UniProtKB-KWPdefense response to virus
GO:0035556 TAS:GOCPintracellular signal transduction
GO:0030336 IMP:UniProtKBPnegative regulation of cell migration
GO:0008285 IMP:UniProtKBPnegative regulation of cell proliferation
GO:0046597 IDA:UniProtKBPnegative regulation of viral entry into host cell
GO:0045071 IDA:UniProtKBPnegative regulation of viral genome replication
GO:0001503 IEA:UniProtKB-KWPossification
GO:0045669 IMP:UniProtKBPpositive regulation of osteoblast differentiation
GO:0050776 TAS:ReactomePregulation of immune response
GO:0035455 IDA:UniProtKBPresponse to interferon-alpha
GO:0035456 IDA:UniProtKBPresponse to interferon-beta
GO:0034341 IDA:UniProtKBPresponse to interferon-gamma
GO:0009615 IDA:UniProtKBPresponse to virus
GO:0060337 TAS:ReactomePtype I interferon signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75774Adaptive Immune System
REACT_75790Cytokine Signaling in Immune system
REACT_6900Immune System
REACT_11152Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
REACT_25162Interferon alpha/beta signaling
REACT_25229Interferon Signaling
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