MGP Database

MGP003586

Record overview

MGPD IDMGP003586
Gene ID8528
SpeciesHomo sapiens (Human)
Gene NameD-aspartate oxidase
Gene Symbol DDO
SynonymsDASOX; DDO-1; DDO-2;
Alternate namesD-aspartate oxidase; D-aspartate oxidase, DDO; aspartic oxidase;
Chromosome6
Map Location6q21
EC Number1.4.3.1;
SummaryThe protein encoded by this gene is a peroxisomal flavoprotein that catalyzes the oxidative deamination of D-aspartate and N-methyl D-aspartate. Flavin adenine dinucleotide or 6-hydroxyflavin adenine dinucleotide can serve as the cofactor in this reaction. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for DDO

Proteins

D-aspartate oxidase isoform a
Refseq ID:NP_003640
Protein GI:40217815
UniProt ID:Q99489
mRNA ID:NM_003649
Length:369
RefSeq Status:
MRPARHWETRFGARDFGGFQDCFFRDRLMDTARIAVVGAGVVGLSTAVCISKLVPRCSVTIISDKFTPDTTSDVAAGMLIPHTYPDTPIHTQKQWFRETF
NHLFAIANSAEAGDAGVHLVSGWQIFQSTPTEEVPFWADVVLGFRKMTEAELKKFPQYVFGQAFTTLKCECPAYLPWLEKRIKGSGGWTLTRRIEDLWEL
HPSFDIVVNCSGLGSRQLAGDSKIFPVRGQVLQVQAPWVEHFIRDGSGLTYIYPGTSHVTLGGTRQKGDWNLSPDAENSREILSRCCALEPSLHGACNIR
EKVGLRPYRPGVRLQTELLARDGQRLPVVHHYGHGSGGISVHWGTALEAARLVSECVHALRTPIPKSNL
 
D-aspartate oxidase isoform b
Refseq ID:NP_004023
Protein GI:40217827
UniProt ID:Q99489
mRNA ID:NM_004032
Length:310
RefSeq Status:
MRPARHWETRFGARDFGGFQDCFFRDRLMDTARIAVVGAGVVGLSTAVCISKLVPRCSVTIISDKFTPDTTSDVAAGMLIPHTYPDTPIHTQKQWFRETF
NHLFAIANSAEAGDAGVHLVSGIKGSGGWTLTRRIEDLWELHPSFDIVVNCSGLGSRQLAGDSKIFPVRGQVLQVQAPWVEHFIRDGSGLTYIYPGTSHV
TLGGTRQKGDWNLSPDAENSREILSRCCALEPSLHGACNIREKVGLRPYRPGVRLQTELLARDGQRLPVVHHYGHGSGGISVHWGTALEAARLVSECVHA
LRTPIPKSNL
 
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