MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP003598

Record overview

MGPD IDMGP003598
Gene ID8553
SpeciesHomo sapiens (Human)
Gene Namebasic helix-loop-helix family, member e40
Gene Symbol BHLHE40
SynonymsDEC1; HLHB2; BHLHB2; STRA13; Stra14; SHARP-2;
Alternate namesclass E basic helix-loop-helix protein 40; basic helix-loop-helix domain containing, class B, 2; class B basic helix-loop-helix protein 2; differentially expressed in chondrocytes 1; differentially expressed in chondrocytes protein 1; differentiated embryo chondrocyte expressed gene 1; enhancer-of-split and hairy-related protein 2; stimulated by retinoic acid gene 13 protein;
Chromosome3
Map Location3p26
SummaryThis gene encodes a basic helix-loop-helix protein expressed in various tissues. The encoded protein can interact with ARNTL or compete for E-box binding sites in the promoter of PER1 and repress CLOCK/ARNTL's transactivation of PER1. This gene is believed to be involved in the control of circadian rhythm and cell differentiation. [provided by RefSeq, Feb 2014]
OrthologsView orthologs and multiple alignments for BHLHE40

Proteins

class E basic helix-loop-helix protein 40
Refseq ID:NP_003661
Protein GI:4503299
UniProt ID:O14503
mRNA ID:NM_003670
Length:412
RefSeq Status:
MERIPSAQPPPACLPKAPGLEHGDLPGMYPAHMYQVYKSRRGIKRSEDSKETYKLPHRLIEKKRRDRINECIAQLKDLLPEHLKLTTLGHLEKAVVLELT
LKHVKALTNLIDQQQQKIIALQSGLQAGELSGRNVETGQEMFCSGFQTCAREVLQYLAKHENTRDLKSSQLVTHLHRVVSELLQGGTSRKPSDPAPKVMD
FKEKPSSPAKGSEGPGKNCVPVIQRTFAHSSGEQSGSDTDTDSGYGGESEKGDLRSEQPCFKSDHGRRFTMGERIGAIKQESEEPPTKKNRMQLSDDEGH
FTSSDLISSPFLGPHPHQPPFCLPFYLIPPSATAYLPMLEKCWYPTSVPVLYPGLNASAAALSSFMNPDKISAPLLMPQRLPSPLPAHPSVDSSVLLQAL
KPIPPLNLETKD
 
  logo