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MGP003605

Record overview

MGPD IDMGP003605
Gene ID8566
SpeciesHomo sapiens (Human)
Gene Namepyridoxal (pyridoxine, vitamin B6) kinase
Gene Symbol PDXK
SynonymsPKH; PNK; PRED79; C21orf97; HEL-S-1a; C21orf124;
Alternate namespyridoxal kinase; epididymis secretory sperm binding protein Li 1a; pyridoxamine kinase; pyridoxine kinase; vitamin B6 kinase;
Chromosome21
Map Location21q22.3
EC Number2.7.1.35
SummaryThe protein encoded by this gene phosphorylates vitamin B6, a step required for the conversion of vitamin B6 to pyridoxal-5-phosphate, an important cofactor in intermediary metabolism. The encoded protein is cytoplasmic and probably acts as a homodimer. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for PDXK

Proteins

pyridoxal kinase
Refseq ID:NP_003672
Protein GI:4505701
UniProt ID:O00764
mRNA ID:NM_003681
Length:312
RefSeq Status:
MEEECRVLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSDELQELYEGLRLNNMNKYDYVLTGYTRDKSFLAMVVDIVQE
LKQQNPRLVYVCDPVLGDKWDGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVVITSSDLPSPQGSNYLI
VLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAMLLAWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQAGEGVRPSPMQLELRMVQSKRDI
EDPEIVVQATVL
 
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