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MGP003663

Record overview

MGPD IDMGP003663
Gene ID8724
SpeciesHomo sapiens (Human)
Gene Namesorting nexin 3
Gene Symbol SNX3
SynonymsSDP3; Grd19; MCOPS8;
Alternate namessorting nexin-3; sorting nexin 3A;
Chromosome6
Map Location6q21
SummaryThis gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like most family members. This protein interacts with phosphatidylinositol-3-phosphate, and is involved in protein trafficking. A pseudogene of this gene is present on the sex chromosomes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]
OrthologsView orthologs and multiple alignments for SNX3

Proteins

sorting nexin-3 isoform a
Refseq ID:NP_003786
Protein GI:4507143
UniProt ID:O60493
mRNA ID:NM_003795
Length:162
RefSeq Status:
MAETVADTRRLITKPQNLNDAYGPPSNFLEIDVSNPQTVGVGRGRFTTYEIRVKTNLPIFKLKESTVRRRYSDFEWLRSELERESKVVVPPLPGKAFLRQ
LPFRGDDGIFDDNFIEERKQGLEQFINKVAGHPLAQNERCLHMFLQDEIIDKSYTPSKIRHA
 
sorting nexin-3 isoform b
Refseq ID:NP_690040
Protein GI:23111041
UniProt ID:O60493
mRNA ID:NM_152827
Length:130
RefSeq Status:
MAETVADTRRLITKPQNLNDAYGPPSNFLEIDVSNPQTVGVGRGRFTTYEIRVKVVVPPLPGKAFLRQLPFRGDDGIFDDNFIEERKQGLEQFINKVAGH
PLAQNERCLHMFLQDEIIDKSYTPSKIRHA
 
sorting nexin-3 isoform c
Refseq ID:NP_001287857
Protein GI:665505963
UniProt ID:
mRNA ID:NM_001300928
Length:105
RefSeq Status:
MAETVADTRRLITKPQNLNDAYGPPSNFLEIDVSNPQTVGVGRGRFTTYEIRVKTNLPIFKLKESTVRRRYSDFEWLRSELERESKGRWSSSGTERTLSS
HVFTR
 
sorting nexin-3 isoform d
Refseq ID:NP_001287858
Protein GI:665505924
UniProt ID:O60493
mRNA ID:NM_001300929
Length:140
RefSeq Status:
MAETVADTRRLITKPQNLNDAYGPPSNFLEIDTNLPIFKLKESTVRRRYSDFEWLRSELERESKVVVPPLPGKAFLRQLPFRGDDGIFDDNFIEERKQGL
EQFINKVAGHPLAQNERCLHMFLQDEIIDKSYTPSKIRHA
 
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