MGP Database

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MGP003668

Record overview

MGPD IDMGP003668
Gene ID8733
SpeciesHomo sapiens (Human)
Gene Nameglycosylphosphatidylinositol anchor attachment 1
Gene Symbol GPAA1
SynonymsGAA1; hGAA1;
Alternate namesglycosylphosphatidylinositol anchor attachment 1 protein; GAA1 protein homolog; GPAA1P anchor attachment protein 1 homolog; GPI anchor attachment protein 1; GPI transamidase subunit; anchor attachment protein 1 (Gaa1p, yeast) homolog; glycophosphatidylinositol anchor attachment 1; glycosylphosphatidylinositol anchor attachment protein 1 homolog;
Chromosome8
Map Location8q24.3
SummaryPosttranslational glycosylphosphatidylinositol (GPI) anchor attachment serves as a general mechanism for linking proteins to the cell surface membrane. The protein encoded by this gene presumably functions in GPI anchoring at the GPI transfer step. The mRNA transcript is ubiquitously expressed in both fetal and adult tissues. The anchor attachment protein 1 contains an N-terminal signal sequence, 1 cAMP- and cGMP-dependent protein kinase phosphorylation site, 1 leucine zipper pattern, 2 potential N-glycosylation sites, and 8 putative transmembrane domains. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for GPAA1

Proteins

glycosylphosphatidylinositol anchor attachment 1 protein
Refseq ID:NP_003792
Protein GI:4504079
UniProt ID:O43292
mRNA ID:NM_003801
Length:621
RefSeq Status:
MGLLSDPVRRRALARLVLRLNAPLCVLSYVAGIAWFLALVFPPLTQRTYMSENAMGSTMVEEQFAGGDRARAFARDFAAHRKKSGALPVAWLERTMRSVG
LEVYTQSFSRKLPFPDETHERYMVSGTNVYGILRAPRAASTESLVLTVPCGSDSTNSQAVGLLLALAAHFRGQIYWAKDIVFLVTEHDLLGTEAWLEAYH
DVNVTGMQSSPLQGRAGAIQAAVALELSSDVVTSLDVAVEGLNGQLPNLDLLNLFQTFCQKGGLLCTLQGKLQPEDWTSLDGPLQGLQTLLLMVLRQASG
RPHGSHGLFLRYRVEALTLRGINSFRQYKYDLVAVGKALEGMFRKLNHLLERLHQSFFLYLLPGLSRFVSIGLYMPAVGFLLLVLGLKALELWMQLHEAG
MGLEEPGGAPGPSVPLPPSQGVGLASLVAPLLISQAMGLALYVLPVLGQHVATQHFPVAEAEAVVLTLLAIYAAGLALPHNTHRVVSTQAPDRGWMALKL
VALIYLALQLGCIALTNFSLGFLLATTMVPTAALAKPHGPRTLYAALLVLTSPAATLLGSLFLWRELQEAPLSLAEGWQLFLAALAQGVLEHHTYGALLF
PLLSLGLYPCWLLFWNVLFWK
 
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