MGP Database

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MGP003676

Ontology/Pathway Information

Entrez Gene ID8754
Gene NameADAM metallopeptidase domain 9
Gene Symbol ADAM9
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0016323 IEA:EnsemblCbasolateral plasma membrane
GO:0009986 ISS:BHF-UCLCcell surface
GO:0005737 IEA:EnsemblCcytoplasm
GO:0005615 IDA:BHF-UCLCextracellular space
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005925 IDA:UniProtKBCfocal adhesion
GO:0016021 IEA:UniProtKB-KWCintegral component of membrane
GO:0031233 ISS:BHF-UCLCintrinsic component of external side of plasma membrane
GO:0005518 IMP:BHF-UCLFcollagen binding
GO:0005178 IDA:BHF-UCLFintegrin binding
GO:0043236 IMP:BHF-UCLFlaminin binding
GO:0004222 IDA:BHF-UCLFmetalloendopeptidase activity
GO:0008237 IMP:BHF-UCLFmetallopeptidase activity
GO:0005080 ISS:BHF-UCLFprotein kinase C binding
GO:0017124 IPI:BHF-UCLFSH3 domain binding
GO:0008270 IEA:InterProFzinc ion binding
GO:0000186 IDA:BHF-UCLPactivation of MAPKK activity
GO:0007155 IMP:BHF-UCLPcell adhesion
GO:0033627 IMP:BHF-UCLPcell adhesion mediated by integrin
GO:0033631 IEP:BHF-UCLPcell-cell adhesion mediated by integrin
GO:0007160 IMP:BHF-UCLPcell-matrix adhesion
GO:0071222 IMP:BHF-UCLPcellular response to lipopolysaccharide
GO:0030574 TAS:ReactomePcollagen catabolic process
GO:0022617 TAS:ReactomePextracellular matrix disassembly
GO:0030198 TAS:ReactomePextracellular matrix organization
GO:0007229 IC:BHF-UCLPintegrin-mediated signaling pathway
GO:0030216 IEP:BHF-UCLPkeratinocyte differentiation
GO:0006509 IDA:BHF-UCLPmembrane protein ectodomain proteolysis
GO:0042117 IMP:BHF-UCLPmonocyte activation
GO:0051088 IDA:BHF-UCLPPMA-inducible membrane protein ectodomain proteolysis
GO:0033630 IMP:BHF-UCLPpositive regulation of cell adhesion mediated by integrin
GO:0051549 IMP:BHF-UCLPpositive regulation of keratinocyte migration
GO:0034241 IMP:BHF-UCLPpositive regulation of macrophage fusion
GO:0051044 ISS:BHF-UCLPpositive regulation of membrane protein ectodomain proteolysis
GO:0050714 IDA:BHF-UCLPpositive regulation of protein secretion
GO:0051592 IMP:BHF-UCLPresponse to calcium ion
GO:0051384 ISS:BHF-UCLPresponse to glucocorticoid
GO:0042542 IMP:BHF-UCLPresponse to hydrogen peroxide
GO:0034616 IEA:EnsemblPresponse to laminar fluid shear stress
GO:0010042 IMP:BHF-UCLPresponse to manganese ion
GO:0034612 IDA:BHF-UCLPresponse to tumor necrosis factor
GO:0007179 IMP:BHF-UCLPtransforming growth factor beta receptor signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_150401Collagen degradation
REACT_118572Degradation of the extracellular matrix
REACT_118779Extracellular matrix organization
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