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MGP003688

UniProt Annotations

Entry Information
Gene Namedelta-like 1 homolog (Drosophila)
Protein EntryDLK1_HUMAN
UniProt IDP80370
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Comment=Additional isoforms seem to exist.; Name=Long; IsoId=P80370-1; Sequence=Displayed; Name=Short; IsoId=P80370-2; Sequence=VSP_001377;
FunctionMay have a role in neuroendocrine differentiation.
PtmN- and O-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans. {ECO:0000269|PubMed:22171320, ECO:0000269|PubMed:7925474}.
Sequence CautionSequence=CAA35582.1; Type=Frameshift; Positions=22, 108, 199; Evidence={ECO:0000305};
SimilarityContains 6 EGF-like domains. {ECO:0000255|PROSITE- ProRule:PRU00076}.
Subcellular LocationMembrane; Single-pass type I membrane protein.
SubunitMonomer.
Tissue SpecificityFound within the stromal cells in close contact to the vascular structure of placental villi, yolk sac, fetal liver, adrenal cortex and pancreas and in the beta cells of the islets of Langerhans in the adult pancreas. Found also in some forms of neuroendocrine lung tumor tissue.
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