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MGP003690

UniProt Annotations

Entry Information
Gene Namefucose-1-phosphate guanylyltransferase
Protein EntryFPGT_HUMAN
UniProt IDO14772
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=6; Name=2; IsoId=O14772-1; Sequence=Displayed; Name=1; IsoId=Q59H18-1; Sequence=External; Note=Based on a naturally occurring readthrough transcript which produces a FPGT-TNNI3K fusion protein.; Name=3; IsoId=Q59H18-3; Sequence=External; Note=Based on a naturally occurring readthrough transcript which produces a FPGT-TNNI3K fusion protein.; Name=4; IsoId=Q59H18-4; Sequence=External; Note=Based on a naturally occurring readthrough transcript which produces a FPGT-TNNI3K fusion protein.; Name=5; IsoId=O14772-2; Sequence=VSP_045076; Note=No experimental confirmation available.; Name=6; IsoId=O14772-3; Sequence=VSP_046460; Note=No experimental confirmation available.;
Catalytic ActivityGTP + beta-L-fucose 1-phosphate = diphosphate + GDP-L-fucose.
FunctionCatalyzes the formation of GDP-L-fucose from GTP and L- fucose-1-phosphate. Functions as a salvage pathway to reutilize L- fucose arising from the turnover of glycoproteins and glycolipids.
Sequence CautionSequence=BAG65299.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305};
Subcellular LocationCytoplasm.
Tissue SpecificityExpressed in many tissues.
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