MGP Database

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MGP003695

Ontology/Pathway Information

Entrez Gene ID8802
Gene Namesuccinate-CoA ligase, alpha subunit
Gene Symbol SUCLG1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:HPACcytoplasm
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005743 IEA:EnsemblCmitochondrial inner membrane
GO:0005759 TAS:ReactomeCmitochondrial matrix
GO:0005739 IDA:HPACmitochondrion
GO:0005886 IDA:HPACplasma membrane
GO:0045244 IEA:EnsemblCsuccinate-CoA ligase complex (GDP-forming)
GO:0003878 IEA:InterProFATP citrate synthase activity
GO:0048037 IEA:InterProFcofactor binding
GO:0019003 IEA:EnsemblFGDP binding
GO:0005525 IEA:UniProtKB-KWFGTP binding
GO:0044822 IDA:UniProtKBFpoly(A) RNA binding
GO:0004775 IEA:UniProtKB-ECFsuccinate-CoA ligase (ADP-forming) activity
GO:0004776 IEA:UniProtKB-ECFsuccinate-CoA ligase (GDP-forming) activity
GO:0044237 TAS:ReactomePcellular metabolic process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0006105 IEA:EnsemblPsuccinate metabolic process
GO:0006104 IEA:EnsemblPsuccinyl-CoA metabolic process
GO:0006099 TAS:ReactomePtricarboxylic acid cycle
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_1785Citric acid cycle (TCA cycle)
REACT_111217Metabolism
REACT_1046Pyruvate metabolism and Citric Acid (TCA) cycle
REACT_111083The citric acid (TCA) cycle and respiratory electron transport
SMP Pathway Links
SMP IDDescription
SMP005492-ketoglutarate dehydrogenase complex deficiency
SMP00057Citric Acid Cycle
SMP00546Congenital lactic acidosis
SMP00547Fumarase deficiency
SMP00548Mitochondrial complex II deficiency
SMP00551Pyruvate dehydrogenase deficiency (E2)
SMP00550Pyruvate dehydrogenase deficiency (E3)
SMP00654Warburg Effect
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