MGP Database

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MGP003702

Ontology/Pathway Information

Entrez Gene ID8818
Gene Namedolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
Gene Symbol DPM2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0033185 IDA:UniProtKBCdolichol-phosphate-mannose synthase complex
GO:0005789 TAS:HGNCCendoplasmic reticulum membrane
GO:0000506 TAS:HGNCCglycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex
GO:0030176 IEA:InterProCintegral component of endoplasmic reticulum membrane
GO:0048471 IEA:EnsemblCperinuclear region of cytoplasm
GO:0004582 IEA:EnsemblFdolichyl-phosphate beta-D-mannosyltransferase activity
GO:0030234 IBA:GO_CentralFenzyme regulator activity
GO:0044267 TAS:ReactomePcellular protein metabolic process
GO:0006501 TAS:ReactomePC-terminal protein lipidation
GO:0006488 TAS:ReactomePdolichol-linked oligosaccharide biosynthetic process
GO:0019348 IBA:GO_CentralPdolichol metabolic process
GO:0006506 IDA:UniProtKBPGPI anchor biosynthetic process
GO:0043687 TAS:ReactomePpost-translational protein modification
GO:0016254 TAS:ReactomePpreassembly of GPI anchor in ER membrane
GO:0018279 TAS:ReactomePprotein N-linked glycosylation via asparagine
GO:0035269 TAS:HGNCPprotein O-linked mannosylation
GO:0031647 IPI:UniProtKBPregulation of protein stability
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_22426Asparagine N-linked glycosylation
REACT_22433Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
REACT_268132Defective ALG11 causes ALG11-CDG (CDG-1p)
REACT_267773Defective ALG12 causes ALG12-CDG (CDG-1g)
REACT_268645Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)
REACT_268144Defective ALG1 causes ALG1-CDG (CDG-1k)
REACT_268833Defective ALG2 causes ALG2-CDG (CDG-1i)
REACT_268185Defective ALG3 causes ALG3-CDG (CDG-1d)
REACT_267765Defective ALG6 causes ALG6-CDG (CDG-1c)
REACT_268459Defective ALG8 causes ALG8-CDG (CDG-1h)
REACT_268015Defective ALG9 causes ALG9-CDG (CDG-1l)
REACT_268438Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)
REACT_268849Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2
REACT_268813Defective MAN1B1 causes MRT15
REACT_268600Defective MGAT2 causes MGAT2-CDG (CDG-2a)
REACT_267905Defective MOGS causes MOGS-CDG (CDG-2b)
REACT_268619Defective MPDU1 causes MPDU1-CDG (CDG-1f)
REACT_268458Defective RFT1 causes RFT1-CDG (CDG-1n)
REACT_116125Disease
REACT_267875Diseases associated with N-glycosylation of proteins
REACT_268324Diseases of glycosylation
REACT_17015Metabolism of proteins
REACT_1853Post-translational modification: synthesis of GPI-anchored proteins
REACT_22161Post-translational protein modification
REACT_2032Synthesis of dolichyl-phosphate mannose
REACT_952Synthesis of glycosylphosphatidylinositol (GPI)
REACT_22387Synthesis of substrates in N-glycan biosythesis
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