MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP003707

Ontology/Pathway Information

Entrez Gene ID8826
Gene NameIQ motif containing GTPase activating protein 1
Gene Symbol IQGAP1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005884 TAS:ProtIncCactin filament
GO:0030424 ISS:UniProtKBCaxon
GO:0030054 IDA:HPACcell junction
GO:0031252 IEA:EnsemblCcell leading edge
GO:0005737 IDA:HPACcytoplasm
GO:0036464 IDA:ParkinsonsUK-UCLCcytoplasmic ribonucleoprotein granule
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0031234 IDA:UniProtKBCextrinsic component of cytoplasmic side of plasma membrane
GO:0005925 IDA:UniProtKBCfocal adhesion
GO:0030426 ISS:UniProtKBCgrowth cone
GO:0016328 IEA:EnsemblClateral plasma membrane
GO:0005874 IDA:UniProtKBCmicrotubule
GO:0030496 IDA:UniProtKBCmidbody
GO:0043005 ISS:UniProtKBCneuron projection
GO:0005654 IDA:HPACnucleoplasm
GO:0005886 IDA:HPACplasma membrane
GO:0036057 ISS:UniProtKBCslit diaphragm
GO:0005509 TAS:BHF-UCLFcalcium ion binding
GO:0005516 IPI:BHF-UCLFcalmodulin binding
GO:0005096 TAS:ProtIncFGTPase activator activity
GO:0005095 TAS:ProtIncFGTPase inhibitor activity
GO:0005547 IDA:UniProtKBFphosphatidylinositol-3,4,5-trisphosphate binding
GO:0019901 IPI:BHF-UCLFprotein kinase binding
GO:0019903 IPI:UniProtKBFprotein phosphatase binding
GO:0043539 IDA:BHF-UCLFprotein serine/threonine kinase activator activity
GO:0005099 IEA:InterProFRas GTPase activator activity
GO:0071277 IDA:BHF-UCLPcellular response to calcium ion
GO:0071364 IMP:BHF-UCLPcellular response to epidermal growth factor stimulus
GO:0006112 TAS:ReactomePenergy reserve metabolic process
GO:0007173 IMP:BHF-UCLPepidermal growth factor receptor signaling pathway
GO:0072015 ISS:UniProtKBPglomerular visceral epithelial cell development
GO:0043086 TAS:GOCPnegative regulation of catalytic activity
GO:0035305 IEA:EnsemblPnegative regulation of dephosphorylation
GO:1990138 IMP:UniProtKBPneuron projection extension
GO:0043547 TAS:GOCPpositive regulation of GTPase activity
GO:0045860 IMP:BHF-UCLPpositive regulation of protein kinase activity
GO:0071902 IDA:GOCPpositive regulation of protein serine/threonine kinase activity
GO:0001817 IEA:EnsemblPregulation of cytokine production
GO:0050796 TAS:ReactomePregulation of insulin secretion
GO:0007165 TAS:ProtIncPsignal transduction
GO:0007264 IEA:InterProPsmall GTPase mediated signal transduction
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_111155Cell-Cell communication
REACT_18274Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
REACT_1505Integration of energy metabolism
REACT_111217Metabolism
REACT_23832Nephrin interactions
REACT_18325Regulation of insulin secretion
  logo