MGP Database

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MGP003711

Ontology/Pathway Information

Entrez Gene ID8833
Gene Nameguanine monphosphate synthase
Gene Symbol GMPS
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:HPACcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0003921 TAS:ProtIncFGMP synthase activity
GO:0003922 IEA:UniProtKB-ECFGMP synthase (glutamine-hydrolyzing) activity
GO:0016462 IEA:InterProFpyrophosphatase activity
GO:0006541 IEA:UniProtKB-KWPglutamine metabolic process
GO:0055086 TAS:ReactomePnucleobase-containing small molecule metabolic process
GO:0009113 TAS:ProtIncPpurine nucleobase biosynthetic process
GO:0006144 TAS:ReactomePpurine nucleobase metabolic process
GO:0009168 TAS:ReactomePpurine ribonucleoside monophosphate biosynthetic process
GO:0042493 IEA:EnsemblPresponse to drug
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_111217Metabolism
REACT_1698Metabolism of nucleotides
REACT_522Purine metabolism
REACT_1776Purine ribonucleoside monophosphate biosynthesis
SMP Pathway Links
SMP IDDescription
SMP001362-Hydroxyglutric Aciduria (D And L Form)
SMP002434-Hydroxybutyric Aciduria/Succinic Semialdehyde Dehydrogenase Deficiency
SMP00535Adenine phosphoribosyltransferase deficiency (APRT)
SMP00144Adenosine Deaminase Deficiency
SMP00167Adenylosuccinate Lyase Deficiency
SMP00168AICA-Ribosiduria
SMP00427Azathioprine Action Pathway
SMP00072Glutamate Metabolism
SMP00365Gout or Kelley-Seegmiller Syndrome
SMP00385Homocarnosinosis
SMP00339Hyperinsulinism-Hyperammonemia Syndrome
SMP00364Lesch-Nyhan Syndrome (LNS)
SMP00428Mercaptopurine Action Pathway
SMP00609Mercaptopurine Metabolism Pathway
SMP00536Mitochondrial DNA depletion syndrome
SMP00203Molybdenum Cofactor Deficiency
SMP00537Myoadenylate deaminase deficiency
SMP00050Purine Metabolism
SMP00210Purine Nucleoside Phosphorylase Deficiency
SMP00567Succinic semialdehyde dehydrogenase deficiency
SMP00430Thioguanine Action Pathway
SMP00220Xanthine Dehydrogenase Deficiency (Xanthinuria)
SMP00512Xanthinuria type I
SMP00513Xanthinuria type II
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