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MGP003713

Record overview

MGPD IDMGP003713
Gene ID8836
SpeciesHomo sapiens (Human)
Gene Namegamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
Gene Symbol GGH
SynonymsGH;
Alternate namesgamma-glutamyl hydrolase; gamma-Glu-X carboxypeptidase;
Chromosome8
Map Location8q12.3
EC Number3.4.19.9
SummaryThis gene catalyzes the hydrolysis of folylpoly-gamma-glutamates and antifolylpoly-gamma-glutamates by the removal of gamma-linked polyglutamates and glutamate. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for GGH

Proteins

gamma-glutamyl hydrolase precursor
Refseq ID:NP_003869
Protein GI:4503987
UniProt ID:Q92820
mRNA ID:NM_003878
Length:318
RefSeq Status:
MASPGCLLCVLGLLLCGAASLELSRPHGDTAKKPIIGILMQKCRNKVMKNYGRYYIAASYVKYLESAGARVVPVRLDLTEKDYEILFKSINGILFPGGSV
DLRRSDYAKVAKIFYNLSIQSFDDGDYFPVWGTCLGFEELSLLISGECLLTATDTVDVAMPLNFTGGQLHSRMFQNFPTELLLSLAVEPLTANFHKWSLS
VKNFTMNEKLKKFFNVLTTNTDGKIEFISTMEGYKYPVYGVQWHPEKAPYEWKNLDGISHAPNAVKTAFYLAEFFVNEARKNNHHFKSESEEEKALIYQF
SPIYTGNISSFQQCYIFD
 
sig_peptide: 1..24
calculated_mol_wt: 2335
peptide sequence: 
MASPGCLLCVLGLLLCGAASLELS

mat_peptide: 25..318
product: gamma-glutamyl hydrolase
calculated_mol_wt: 33648
peptide sequence: 
RPHGDTAKKPIIGILMQKCRNKVMKNYGRYYIAASYVKYLESAGARVVPVRLDLTEKDYEILFKSINGILFPGGSVDLRRSDYAKVAKIFYNLSIQSFDD
GDYFPVWGTCLGFEELSLLISGECLLTATDTVDVAMPLNFTGGQLHSRMFQNFPTELLLSLAVEPLTANFHKWSLSVKNFTMNEKLKKFFNVLTTNTDGK
IEFISTMEGYKYPVYGVQWHPEKAPYEWKNLDGISHAPNAVKTAFYLAEFFVNEARKNNHHFKSESEEEKALIYQFSPIYTGNISSFQQCYIFD
 
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