MGP Database

MGP003719

Ontology/Pathway Information

Entrez Gene ID	8854
Gene Name	aldehyde dehydrogenase 1 family, member A2
Gene Symbol	ALDH1A2
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005737	IDA:UniProtKB	C	cytoplasm
GO:0005829	IEA:Ensembl	C	cytosol
GO:0048471	IEA:Ensembl	C	perinuclear region of cytoplasm
GO:0004028	ISS:UniProtKB	F	3-chloroallyl aldehyde dehydrogenase activity
GO:0004029	IBA:GO_Central	F	aldehyde dehydrogenase (NAD) activity
GO:0016918	ISS:UniProtKB	F	retinal binding
GO:0001758	ISS:UniProtKB	F	retinal dehydrogenase activity
GO:0042904	IEA:Ensembl	P	9-cis-retinoic acid biosynthetic process
GO:0009952	IEA:Ensembl	P	anterior/posterior pattern specification
GO:0001568	IEA:Ensembl	P	blood vessel development
GO:0048738	IEA:Ensembl	P	cardiac muscle tissue development
GO:0071300	IEA:Ensembl	P	cellular response to retinoic acid
GO:0009855	IEA:Ensembl	P	determination of bilateral symmetry
GO:0031076	IEA:Ensembl	P	embryonic camera-type eye development
GO:0048566	IEA:Ensembl	P	embryonic digestive tract development
GO:0035115	IEA:Ensembl	P	embryonic forelimb morphogenesis
GO:0060324	IEA:Ensembl	P	face development
GO:0003007	IEA:Ensembl	P	heart morphogenesis
GO:0030902	IEA:Ensembl	P	hindbrain development
GO:0001822	IEA:Ensembl	P	kidney development
GO:0001889	IEA:Ensembl	P	liver development
GO:0030324	IEA:Ensembl	P	lung development
GO:0007494	IEA:Ensembl	P	midgut development
GO:0016331	IEA:Ensembl	P	morphogenesis of embryonic epithelium
GO:0008285	IDA:UniProtKB	P	negative regulation of cell proliferation
GO:0014032	IEA:Ensembl	P	neural crest cell development
GO:0021915	IMP:UniProtKB	P	neural tube development
GO:0030182	IEA:Ensembl	P	neuron differentiation
GO:0031016	IEA:Ensembl	P	pancreas development
GO:0021983	IEA:Ensembl	P	pituitary gland development
GO:0043065	IEA:Ensembl	P	positive regulation of apoptotic process
GO:0008284	IEA:Ensembl	P	positive regulation of cell proliferation
GO:0010628	IEA:Ensembl	P	positive regulation of gene expression
GO:0009954	IEA:Ensembl	P	proximal/distal pattern formation
GO:0001936	IEA:Ensembl	P	regulation of endothelial cell proliferation
GO:0034097	IDA:UniProtKB	P	response to cytokine
GO:0032355	IEA:Ensembl	P	response to estradiol
GO:0033189	IEA:Ensembl	P	response to vitamin A
GO:0042574	IEA:Ensembl	P	retinal metabolic process
GO:0042573	ISS:UniProtKB	P	retinoic acid metabolic process
GO:0048384	IEA:Ensembl	P	retinoic acid receptor signaling pathway
GO:0042572	IEA:UniProtKB-UniPathway	P	retinol metabolic process
GO:0035799	IEA:Ensembl	P	ureter maturation
GO:0006776	NAS:UniProtKB	P	vitamin A metabolic process

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_268561	RA biosynthesis pathway
REACT_267785	Signaling by Retinoic Acid
REACT_111102	Signal Transduction

SMP Pathway Links

SMP ID	Description
SMP00074	Retinol Metabolism
SMP00336	Vitamin A Deficiency