MGP Database

MGP003751

Ontology/Pathway Information

Entrez Gene ID	8932
Gene Name	methyl-CpG binding domain protein 2
Gene Symbol	MBD2
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005737	IEA:Ensembl	C	cytoplasm
GO:0000792	IEA:Ensembl	C	heterochromatin
GO:0000118	IEA:Ensembl	C	histone deacetylase complex
GO:0000790	IDA:UniProtKB	C	nuclear chromatin
GO:0005634	IDA:UniProtKB	C	nucleus
GO:0043234	IDA:UniProtKB	C	protein complex
GO:0070742	IPI:UniProtKB	F	C2H2 zinc finger domain binding
GO:0003682	IEA:Ensembl	F	chromatin binding
GO:0008327	IDA:UniProtKB	F	methyl-CpG binding
GO:0003729	IEA:Ensembl	F	mRNA binding
GO:0019904	IPI:UniProtKB	F	protein domain specific binding
GO:0003696	TAS:ProtInc	F	satellite DNA binding
GO:0035197	IEA:Ensembl	F	siRNA binding
GO:0043044	IDA:UniProtKB	P	ATP-dependent chromatin remodeling
GO:0043623	IEA:Ensembl	P	cellular protein complex assembly
GO:0042711	IEA:Ensembl	P	maternal behavior
GO:0045892	NAS:UniProtKB	P	negative regulation of transcription, DNA-templated
GO:0000122	IEA:Ensembl	P	negative regulation of transcription from RNA polymerase II promoter
GO:0030177	IEA:Ensembl	P	positive regulation of Wnt signaling pathway
GO:0042127	IEA:Ensembl	P	regulation of cell proliferation
GO:0006351	IEA:UniProtKB-KW	P	transcription, DNA-templated

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_264098	Epigenetic regulation of gene expression
REACT_71	Gene Expression
REACT_264000	Negative epigenetic regulation of rRNA expression
REACT_263965	NoRC negatively regulates rRNA expression
REACT_1974	RNA Polymerase I Promoter Clearance
REACT_2232	RNA Polymerase I Promoter Opening
REACT_21352	RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
REACT_1309	RNA Polymerase I Transcription