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MGP003784

Record overview

MGPD IDMGP003784
Gene ID9056
SpeciesHomo sapiens (Human)
Gene Namesolute carrier family 7 (amino acid transporter light chain, y+L system), member 7
Gene Symbol SLC7A7
SynonymsLPI; LAT3; MOP-2; Y+LAT1; y+LAT-1;
Alternate namesY+L amino acid transporter 1; monocyte amino acid permease 2; solute carrier family 7 (cationic amino acid transporter, y+ system), member 7; y(+)L-type amino acid transporter 1;
Chromosome14
Map Location14q11.2
SummaryThe protein encoded by this gene is the light subunit of a cationic amino acid transporter. This sodium-independent transporter is formed when the light subunit encoded by this gene dimerizes with the heavy subunit transporter protein SLC3A2. This transporter is found in epithelial cell membranes where it transfers cationic and large neutral amino acids from the cell to the extracellular space. Defects in this gene are a cause of lysinuric protein intolerance (LPI). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2011]
OrthologsView orthologs and multiple alignments for SLC7A7

Proteins

Y+L amino acid transporter 1
Refseq ID:NP_001119577
Protein GI:186910306
UniProt ID:Q9UM01
mRNA ID:NM_001126105
Length:511
RefSeq Status:
MVDSTEYEVASQPEVETSPLGDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVIWAVGGLFSVFGALCYAELGTTIKKS
GASYAYILEAFGGFLAFIRLWTSLLIIEPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLALIAVIV
AGIVRLGQGASTHFENSFEGSSFAVGDIALALYSALFSYSGWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTF
ADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQ
LYLRWKEPDRPRPLKLSVFFPIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQVLCMSVAAEMDLEDGG
EMPKQRDPKSN
 
Y+L amino acid transporter 1
Refseq ID:NP_001119578
Protein GI:186910308
UniProt ID:Q9UM01
mRNA ID:NM_001126106
Length:511
RefSeq Status:
Protein sequence is identical to GI:186910306 (mRNA isoform)
 
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