MGP Database

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MGP003805

Ontology/Pathway Information

Entrez Gene ID9126
Gene Namestructural maintenance of chromosomes 3
Gene Symbol SMC3
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005604 TAS:ProtIncCbasement membrane
GO:0000785 IDA:UniProtKBCchromatin
GO:0005694 TAS:ReactomeCchromosome
GO:0000775 TAS:ReactomeCchromosome, centromeric region
GO:0008278 NAS:UniProtKBCcohesin complex
GO:0008280 IEA:InterProCcohesin core heterodimer
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0000800 IEA:EnsemblClateral element
GO:0030893 IDA:UniProtKBCmeiotic cohesin complex
GO:0016363 IDA:UniProtKBCnuclear matrix
GO:0034991 IEA:EnsemblCnuclear meiotic cohesin complex
GO:0005654 IDA:HPACnucleoplasm
GO:0005634 TAS:ProtIncCnucleus
GO:0000922 IDA:UniProtKBCspindle pole
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0003682 IEA:EnsemblFchromatin binding
GO:0045502 IDA:UniProtKBFdynein binding
GO:0003777 NAS:UniProtKBFmicrotubule motor activity
GO:0046982 IPI:UniProtKBFprotein heterodimerization activity
GO:0051301 IEA:UniProtKB-KWPcell division
GO:0006281 IEA:UniProtKB-KWPDNA repair
GO:0007126 IDA:UniProtKBPmeiotic nuclear division
GO:0000278 TAS:ReactomePmitotic cell cycle
GO:0007067 TAS:ProtIncPmitotic nuclear division
GO:0007064 IEA:InterProPmitotic sister chromatid cohesion
GO:0007052 IEP:UniProtKBPmitotic spindle organization
GO:0032876 IMP:BHF-UCLPnegative regulation of DNA endoreduplication
GO:0006275 IMP:UniProtKBPregulation of DNA replication
GO:0007165 IDA:UniProtKBPsignal transduction
GO:0007062 NAS:UniProtKBPsister chromatid cohesion
GO:0019827 IEA:EnsemblPstem cell maintenance
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_115566Cell Cycle
REACT_152Cell Cycle, Mitotic
REACT_150421Cohesin Loading onto Chromatin
REACT_150266Establishment of Sister Chromatid Cohesion
REACT_111183Meiosis
REACT_75792Meiotic synapsis
REACT_1275Mitotic Anaphase
REACT_150314Mitotic Metaphase and Anaphase
REACT_682Mitotic Prometaphase
REACT_1932Mitotic Telophase/Cytokinesis
REACT_910M Phase
REACT_150425Resolution of Sister Chromatid Cohesion
REACT_150471Separation of Sister Chromatids
REACT_899S Phase
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