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MGP003808

UniProt Annotations

Entry Information
Gene Namecyclin B2
Protein EntryCCNB2_HUMAN
UniProt IDO95067
SpeciesHuman
Comments
Comment typeDescription
Developmental StageAccumulates steadily during G2 and is abruptly destroyed at mitosis.
FunctionEssential for the control of the cell cycle at the G2/M (mitosis) transition.
InteractionP24941:CDK2; NbExp=2; IntAct=EBI-375024, EBI-375096; P21333:FLNA; NbExp=8; IntAct=EBI-375024, EBI-350432;
SimilarityBelongs to the cyclin family. Cyclin AB subfamily. {ECO:0000305}.
SubunitInteracts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.
Web ResourceName=NIEHS-SNPs; URL="http://egp.gs.washington.edu/data/ccnb2/";
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