MGP Database

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MGP003830

Ontology/Pathway Information

Entrez Gene ID9212
Gene Nameaurora kinase B
Gene Symbol AURKB
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0010369 IEA:EnsemblCchromocenter
GO:0032133 IPI:UniProtKBCchromosome passenger complex
GO:0000779 IDA:UniProtKBCcondensed chromosome, centromeric region
GO:0000780 IDA:BHF-UCLCcondensed nuclear chromosome, centromeric region
GO:0005829 TAS:ReactomeCcytosol
GO:0030496 IDA:UniProtKBCmidbody
GO:0005634 IDA:UniProtKBCnucleus
GO:0005819 TAS:UniProtKBCspindle
GO:0005876 IBA:GO_CentralCspindle microtubule
GO:0051233 IBA:GO_CentralCspindle midzone
GO:0031616 IBA:GO_CentralCspindle pole centrosome
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0035174 ISS:UniProtKBFhistone serine kinase activity
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0004674 IDA:FlyBaseFprotein serine/threonine kinase activity
GO:0004712 TAS:UniProtKBFprotein serine/threonine/tyrosine kinase activity
GO:0009838 ISS:UniProtKBPabscission
GO:0007568 IEA:EnsemblPaging
GO:0031145 TAS:ReactomePanaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0008608 TAS:UniProtKBPattachment of spindle microtubules to kinetochore
GO:0008283 IEA:EnsemblPcell proliferation
GO:0034644 IDA:UniProtKBPcellular response to UV
GO:0036089 IDA:UniProtKBPcleavage furrow formation
GO:0031565 ISS:UniProtKBPcytokinesis checkpoint
GO:0043988 ISS:UniProtKBPhistone H3-S28 phosphorylation
GO:0016570 TAS:UniProtKBPhistone modification
GO:0000278 TAS:ReactomePmitotic cell cycle
GO:0051256 IMP:UniProtKBPmitotic spindle midzone assembly
GO:0002903 IDA:UniProtKBPnegative regulation of B cell apoptotic process
GO:0032466 ISS:UniProtKBPnegative regulation of cytokinesis
GO:0032091 IDA:UniProtKBPnegative regulation of protein binding
GO:0000122 IDA:UniProtKBPnegative regulation of transcription from RNA polymerase II promoter
GO:0032467 IMP:UniProtKBPpositive regulation of cytokinesis
GO:0046777 TAS:UniProtKBPprotein autophosphorylation
GO:0034501 IMP:UniProtKBPprotein localization to kinetochore
GO:0006468 IDA:UniProtKBPprotein phosphorylation
GO:0051983 TAS:UniProtKBPregulation of chromosome segregation
GO:0031577 IEA:InterProPspindle checkpoint
GO:0043146 IMP:UniProtKBPspindle stabilization
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_6761APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
REACT_6828APC/C-mediated degradation of cell cycle proteins
REACT_115566Cell Cycle
REACT_152Cell Cycle, Mitotic
REACT_1275Mitotic Anaphase
REACT_150314Mitotic Metaphase and Anaphase
REACT_682Mitotic Prometaphase
REACT_910M Phase
REACT_21279Regulation of mitotic cell cycle
REACT_150425Resolution of Sister Chromatid Cohesion
REACT_150471Separation of Sister Chromatids
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