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MGP003847

UniProt Annotations

Entry Information
Gene NameG protein-coupled receptor 37 like 1
Protein EntryETBR2_HUMAN
UniProt IDO60883
SpeciesHuman
Comments
Comment typeDescription
FunctionReceptor for the neuroprotective and glioprotective factor prosaposin. Ligand binding induces endocytosis, followed by an ERK phosphorylation cascade. {ECO:0000269|PubMed:23690594}.
InteractionP42785:PRCP; NbExp=2; IntAct=EBI-2927498, EBI-2803892;
PtmO-glycosylated. {ECO:0000269|PubMed:23234360}.
SimilarityBelongs to the G-protein coupled receptor 1 family. {ECO:0000255|PROSITE-ProRule:PRU00521}.
Subcellular LocationCell membrane; Multi-pass membrane protein.
Tissue SpecificityExpressed in the central nervous system.
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