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MGP003877

Record overview

MGPD IDMGP003877
Gene ID9370
SpeciesHomo sapiens (Human)
Gene Nameadiponectin, C1Q and collagen domain containing
Gene Symbol ADIPOQ
SynonymsACDC; ADPN; APM1; APM-1; GBP28; ACRP30; ADIPQTL1;
Alternate namesadiponectin; 30 kDa adipocyte complement-related protein; adipocyte complement-related 30 kDa protein; adipose most abundant gene transcript 1 protein; adipose specific collagen-like factor; gelatin-binding protein 28;
Chromosome3
Map Location3q27
SummaryThis gene is expressed in adipose tissue exclusively. It encodes a protein with similarity to collagens X and VIII and complement factor C1q. The encoded protein circulates in the plasma and is involved with metabolic and hormonal processes. Mutations in this gene are associated with adiponectin deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Apr 2010]
OrthologsView orthologs and multiple alignments for ADIPOQ

Proteins

adiponectin precursor
Refseq ID:NP_001171271
Protein GI:295317372
UniProt ID:Q15848
mRNA ID:NM_001177800
Length:244
RefSeq Status:
MLLLGAVLLLLALPGHDQETTTQGPGVLLPLPKGACTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGLIGPKGDIGETGVPGAEGPRGFPGIQGR
KGEPGEGAYVYRSAFSVGLETYVTIPNMPIRFTKIFYNQQNHYDGSTGKFHCNIPGLYYFAYHITVYMKDVKVSLFKKDKAMLFTYDQYQENNVDQASGS
VLLHLEVGDQVWLQVYGEGERNGLYADNDNDSTFTGFLLYHDTN
 
sig_peptide: 1..14
calculated_mol_wt: 1450
peptide sequence: 
MLLLGAVLLLLALP

mat_peptide: 15..244
product: adiponectin
calculated_mol_wt: 24982
peptide sequence: 
GHDQETTTQGPGVLLPLPKGACTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGLIGPKGDIGETGVPGAEGPRGFPGIQGRKGEPGEGAYVYRSA
FSVGLETYVTIPNMPIRFTKIFYNQQNHYDGSTGKFHCNIPGLYYFAYHITVYMKDVKVSLFKKDKAMLFTYDQYQENNVDQASGSVLLHLEVGDQVWLQ
VYGEGERNGLYADNDNDSTFTGFLLYHDTN
 
adiponectin precursor
Refseq ID:NP_004788
Protein GI:4757760
UniProt ID:Q15848
mRNA ID:NM_004797
Length:244
RefSeq Status:
Protein sequence is identical to GI:295317372 (mRNA isoform)
 
sig_peptide: 1..14
calculated_mol_wt: 1450
peptide sequence: 
MLLLGAVLLLLALP

mat_peptide: 15..244
product: adiponectin
calculated_mol_wt: 24982
peptide sequence: 
GHDQETTTQGPGVLLPLPKGACTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGLIGPKGDIGETGVPGAEGPRGFPGIQGRKGEPGEGAYVYRSA
FSVGLETYVTIPNMPIRFTKIFYNQQNHYDGSTGKFHCNIPGLYYFAYHITVYMKDVKVSLFKKDKAMLFTYDQYQENNVDQASGSVLLHLEVGDQVWLQ
VYGEGERNGLYADNDNDSTFTGFLLYHDTN

sig_peptide: 1..14
calculated_mol_wt: 1450
peptide sequence: 
MLLLGAVLLLLALP

mat_peptide: 15..244
product: adiponectin
calculated_mol_wt: 24982
peptide sequence: 
GHDQETTTQGPGVLLPLPKGACTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGLIGPKGDIGETGVPGAEGPRGFPGIQGRKGEPGEGAYVYRSA
FSVGLETYVTIPNMPIRFTKIFYNQQNHYDGSTGKFHCNIPGLYYFAYHITVYMKDVKVSLFKKDKAMLFTYDQYQENNVDQASGSVLLHLEVGDQVWLQ
VYGEGERNGLYADNDNDSTFTGFLLYHDTN
 
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