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MGP003882

Record overview

MGPD IDMGP003882
Gene ID9380
SpeciesHomo sapiens (Human)
Gene Nameglyoxylate reductase/hydroxypyruvate reductase
Gene Symbol GRHPR
SynonymsPH2; GLXR; GLYD;
Alternate namesglyoxylate reductase/hydroxypyruvate reductase; glycerate-2-dehydrogenase;
Chromosome9
Map Location9q12
EC Number1.1.1.79
SummaryThis gene encodes an enzyme with hydroxypyruvate reductase, glyoxylate reductase, and D-glycerate dehydrogenase enzymatic activities. The enzyme has widespread tissue expression and has a role in metabolism. Type II hyperoxaluria is caused by mutations in this gene. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for GRHPR

Proteins

glyoxylate reductase/hydroxypyruvate reductase
Refseq ID:NP_036335
Protein GI:6912396
UniProt ID:Q9UBQ7
mRNA ID:NM_012203
Length:328
RefSeq Status:
MRPVRLMKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLSDHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRV
GYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFV
STPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHR
TRNTMSLLAANNLLAGLRGEPMPSELKL
 
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