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MGP003915

Record overview

MGPD IDMGP003915
Gene ID9469
SpeciesHomo sapiens (Human)
Gene Namecarbohydrate (chondroitin 6) sulfotransferase 3
Gene Symbol CHST3
SynonymsHSD; C6ST; C6ST1;
Alternate namescarbohydrate sulfotransferase 3; C6ST-1; GST-0; chondroitin 6-O-sulfotransferase 1; galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 0;
Chromosome10
Map Location10q22.1
EC Number2.8.2.17
SummaryThis gene encodes an enzyme which catalyzes the sulfation of chondroitin, a proteoglycan found in the extracellular matrix and most cells which is involved in cell migration and differentiation. Mutations in this gene are associated with spondylepiphyseal dysplasia and humerospinal dysostosis. [provided by RefSeq, Mar 2009]
OrthologsView orthologs and multiple alignments for CHST3

Proteins

carbohydrate sulfotransferase 3
Refseq ID:NP_004264
Protein GI:19923281
UniProt ID:Q7LGC8
mRNA ID:NM_004273
Length:479
RefSeq Status:
MEKGLTLPQDCRDFVHSLKMRSKYALFLVFVVIVFVFIEKENKIISRVSDKLKQIPQALADANSTDPALILAENASLLSLSELDSAFSQLQSRLRNLSLQ
LGVEPAMEAAGEEEEEQRKEEEPPRPAVAGPRRHVLLMATTRTGSSFVGEFFNQQGNIFYLFEPLWHIERTVSFEPGGANAAGSALVYRDVLKQLFLCDL
YVLEHFITPLPEDHLTQFMFRRGSSRSLCEDPVCTPFVKKVFEKYHCKNRRCGPLNVTLAAEACRRKEHMALKAVRIRQLEFLQPLAEDPRLDLRVIQLV
RDPRAVLASRMVAFAGKYKTWKKWLDDEGQDGLREEEVQRLRGNCESIRLSAELGLRQPAWLRGRYMLVRYEDVARGPLQKAREMYRFAGIPLTPQVEDW
IQKNTQAAHDGSGIYSTQKNSSEQFEKWRFSMPFKLAQVVQAACGPAMRLFGYKLARDAAALTNRSVSLLEERGTFWVT
 
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