MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP003920

Record overview

MGPD IDMGP003920
Gene ID9488
SpeciesHomo sapiens (Human)
Gene Namephosphatidylinositol glycan anchor biosynthesis, class B
Gene Symbol PIGB
SynonymsPIG-B; GPI-MT-III;
Alternate namesGPI mannosyltransferase 3; GPI mannosyltransferase III; dol-P-Man dependent GPI mannosyltransferase; phosphatidylinositol glycan, class B; phosphatidylinositol-glycan biosynthesis class B protein;
Chromosome15
Map Location15q21.3
EC Number2.4.1.-
SummaryThis gene encodes a transmembrane protein that is located in the endoplasmic reticulum and is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene is thought to encode a member of a family of dolichol-phosphate-mannose (Dol-P-Man) dependent mannosyltransferases. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for PIGB

Proteins

GPI mannosyltransferase 3
Refseq ID:NP_004846
Protein GI:110224465
UniProt ID:Q92521
mRNA ID:NM_004855
Length:554
RefSeq Status:
MRRPLSKCGMEPGGGDASLTLHGLQNRSHGKIKLRKRKSTLYFNTQEKSARRRGDLLGENIYLLLFTIALRILNCFLVQTSFVPDEYWQSLEVSHHMVFN
YGYLTWEWTERLRSYTYPLIFASIYKILHLLGKDSVQLLIWIPRLAQALLSAVADVRLYSLMKQLENQEVARWVFFCQLCSWFTWYCCTRTLTNTMETVL
TIIALFYYPLEGSKSMNSVKYSSLVALAFIIRPTAVILWTPLLFRHFCQEPRKLDLILHHFLPVGFVTLSLSLMIDRIFFGQWTLVQFNFLKFNVLQNWG
TFYGSHPWHWYFSQGFPVILGTHLPFFIHGCYLAPKRYRILLVTVLWTLLVYSMLSHKEFRFIYPVLPFCMVFCGYSLTHLKTWKKPALSFLFLSNLFLA
LYTGLVHQRGTLDVMSHIQKVCYNNPNKSSASIFIMMPCHSTPYYSHVHCPLPMRFLQCPPDLTGKSHYLDEADVFYLNPLNWLHREFHDDASLPTHLIT
FSILEEEISAFLISSNYKRTAVFFHTHLPEGRIGSHIYVYERKLKGKFNMKMKF
 
  logo