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MGP003932

Record overview

MGPD IDMGP003932
Gene ID9514
SpeciesHomo sapiens (Human)
Gene Namegalactose-3-O-sulfotransferase 1
Gene Symbol GAL3ST1
SynonymsCST;
Alternate namesgalactosylceramide sulfotransferase; 3'-phosphoadenosine-5'-phosphosulfate:GalCer sulfotransferase; 3'-phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase; GalCer sulfotransferase; cerebroside (3'-phosphoadenylylsulfate:galactosylceramide 3') sulfotransferase; cerebroside sulfotransferase;
Chromosome22
Map Location22q12.2
EC Number2.8.2.11
SummarySulfonation, an important step in the metabolism of many drugs, xenobiotics, hormones, and neurotransmitters, is catalyzed by sulfotransferases. The product of this gene is galactosylceramide sulfotransferase which catalyzes the conversion between 3'-phosphoadenylylsulfate + a galactosylceramide to adenosine 3',5'-bisphosphate + galactosylceramide sulfate. Activity of this sulfotransferase is enhanced in renal cell carcinoma. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for GAL3ST1

Proteins

galactosylceramide sulfotransferase
Refseq ID:NP_004852
Protein GI:4758088
UniProt ID:Q99999
mRNA ID:NM_004861
Length:423
RefSeq Status:
MLPPQKKPWESMAKGLVLGALFTSFLLLVYSYAVPPLHAGLASTTPEAAASCSPPALEPEAVIRANGSAGECQPRRNIVFLKTHKTASSTLLNILFRFGQ
KHRLKFAFPNGRNDFDYPTFFARSLVQDYRPGACFNIICNHMRFHYDEVRGLVPTNAIFITVLRDPARLFESSFHYFGPVVPLTWKLSAGDKLTEFLQDP
DRYYDPNGFNAHYLRNLLFFDLGYDNSLDPSSPQVQEHILEVERRFHLVLLQEYFDESLVLLKDLLCWELEDVLYFKLNARRDSPVPRLSGELYGRATAW
NMLDSHLYRHFNASFWRKVEAFGRERMAREVAALRHANERMRTICIDGGHAVDAAAIQDEAMQPWQPLGTKSILGYNLKKSIGQRHAQLCRRMLTPEIQY
LMDLGANLWVTKLWKFIRDFLRW
 
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