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MGP Database

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MGP003933

Ontology/Pathway Information

Entrez Gene ID	9517
Gene Name	serine palmitoyltransferase, long chain base subunit 2
Gene Symbol	SPTLC2
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005789	TAS:Reactome	C	endoplasmic reticulum membrane
GO:0016021	IEA:UniProtKB-KW	C	integral component of membrane
GO:0005739	IEA:Ensembl	C	mitochondrion
GO:0017059	IDA:UniProtKB	C	serine C-palmitoyltransferase complex
GO:0030170	IEA:InterPro	F	pyridoxal phosphate binding
GO:0004758	IDA:UniProtKB	F	serine C-palmitoyltransferase activity
GO:0046513	IEA:Ensembl	P	ceramide biosynthetic process
GO:0044281	TAS:Reactome	P	small molecule metabolic process
GO:0046511	IEA:Ensembl	P	sphinganine biosynthetic process
GO:0030148	TAS:UniProtKB	P	sphingolipid biosynthetic process
GO:0006665	TAS:Reactome	P	sphingolipid metabolic process
GO:0006686	IEA:Ensembl	P	sphingomyelin biosynthetic process
GO:0046512	IEA:Ensembl	P	sphingosine biosynthetic process

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_111217	Metabolism
REACT_22258	Metabolism of lipids and lipoproteins
REACT_115810	Sphingolipid de novo biosynthesis
REACT_19323	Sphingolipid metabolism

SMP Pathway Links

SMP ID	Description
SMP00525	Fabry disease
SMP00349	Gaucher Disease
SMP00348	Globoid Cell Leukodystrophy
SMP00526	Krabbe disease
SMP00347	Metachromatic Leukodystrophy (MLD)
SMP00034	Sphingolipid Metabolism