MGP Database

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MGP004007

Ontology/Pathway Information

Entrez Gene ID9775
Gene Nameeukaryotic translation initiation factor 4A3
Gene Symbol EIF4A3
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0071013 IDA:UniProtKBCcatalytic step 2 spliceosome
GO:0005737 IDA:HGNCCcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0035145 IDA:UniProtKBCexon-exon junction complex
GO:0016020 IDA:UniProtKBCmembrane
GO:0016607 IEA:UniProtKB-SubCellCnuclear speck
GO:0005654 IDA:HPACnucleoplasm
GO:0005524 IDA:HGNCFATP binding
GO:0004004 IDA:HGNCFATP-dependent RNA helicase activity
GO:0003729 IDA:UniProtKBFmRNA binding
GO:0008143 IDA:HGNCFpoly(A) binding
GO:0044822 IDA:UniProtKBFpoly(A) RNA binding
GO:0006200 IDA:GOCPATP catabolic process
GO:0019221 TAS:ReactomePcytokine-mediated signaling pathway
GO:0048701 IMP:UniProtKBPembryonic cranial skeleton morphogenesis
GO:0010467 TAS:ReactomePgene expression
GO:0016071 TAS:ReactomePmRNA metabolic process
GO:0000398 IC:UniProtKBPmRNA splicing, via spliceosome
GO:0051028 IEA:UniProtKB-KWPmRNA transport
GO:0017148 IDA:HGNCPnegative regulation of translation
GO:0000288 TAS:ReactomePnuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000184 IMP:UniProtKBPnuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000289 TAS:ReactomePnuclear-transcribed mRNA poly(A) tail shortening
GO:0045727 IMP:UniProtKBPpositive regulation of translation
GO:0016070 TAS:ReactomePRNA metabolic process
GO:0006364 IEA:UniProtKB-KWPrRNA processing
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_115676Antiviral mechanism by IFN-stimulated genes
REACT_75790Cytokine Signaling in Immune system
REACT_20639Deadenylation-dependent mRNA decay
REACT_20514Deadenylation of mRNA
REACT_71Gene Expression
REACT_6900Immune System
REACT_25229Interferon Signaling
REACT_115831ISG15 antiviral mechanism
REACT_75886Nonsense-Mediated Decay (NMD)
REACT_75822Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
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