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MGP004016

UniProt Annotations

Entry Information
Gene Nameinositol hexakisphosphate kinase 1
Protein EntryIP6K1_HUMAN
UniProt IDQ92551
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q92551-1; Sequence=Displayed; Name=2; IsoId=Q92551-2; Sequence=VSP_042756;
Catalytic ActivityATP + 1D-myo-inositol 1-diphosphate 2,3,4,5,6- pentakisphosphate = ADP + 1D-myo-inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate.
Catalytic ActivityATP + 1D-myo-inositol hexakisphosphate = ADP + 1D-myo-inositol 5-diphosphate 1,2,3,4,6-pentakisphosphate.
FunctionConverts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4.
Sequence CautionSequence=BAA13393.2; Type=Erroneous initiation; Evidence={ECO:0000305};
SimilarityBelongs to the inositol phosphokinase (IPK) family. {ECO:0000305}.
Subcellular LocationCytoplasm {ECO:0000269|PubMed:11502751}. Nucleus {ECO:0000269|PubMed:11502751}.
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